Evidence map›Paper›PMID 30073045›Full record

ArticleStatistical analysis and data mining2018

The next-generation K-means algorithm.

Eugene Demidenko

Abstract read
In one paragraph

Article in Statistical analysis and data mining, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Ovarian Cancer: Multi-Omics Data Integration.International journal of molecular sciences · 2025
    Review
  2. Article
  3. Article
  4. scmNature communications · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. The next-generation K-means algorithm.Statistical analysis and data mining · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Eugene DemidenkoDepartment of Biomedical Data Science and Department of Mathematics Dartmouth College Hanover New Hampshire.ORCID 0000-0002-6584-1148

Funding

Project 3: Direct & Repeated Measurement of pO2 in Deep-seated Tumors using EPR OP01CA190193 · NCI · DARTMOUTH COLLEGE · PI WILLIAMS, BENJAMIN B · 2015 to 2019
$7.0M
Coordinating Center: Molecular and Cellular Findings of Screen-Detected LesionsU01CA196386 · NCI · DARTMOUTH COLLEGE · PI AMOS, CHRISTOPHER I. · 2015 to 2020
$4.1M
A precision medicine basis for estrogen therapy for advanced breast cancerR01CA200994 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI Todd W. Miller · 2017 to 2026
$3.7M
Timing is everything: applications in precision oncology for ER+ breast cancerR01CA211869 · NCI · DARTMOUTH COLLEGE · PI MILLER, TODD W. · 2017 to 2021
$2.1M
Bioinformatics strategies to relate age of onset with gene-gene interactionR01LM012012 · NLM · DARTMOUTH COLLEGE · PI GUI, JIANG · 2015 to 2017
$1.1M
Predicting SNP priors for Cancer GWASsR56LM012371 · NLM · DARTMOUTH COLLEGE · PI DEMIDENKO, EUGENE · 2017 to 2018
$640k
NCI NIH HHS P01 CA190193NCI NIH HHS R01 CA200994NCI NIH HHS R01 CA211869NCI NIH HHS U01 CA196386NLM NIH HHS R01 LM012012NLM NIH HHS R56 LM012371
6 · The paper itself

Abstract

Typically, when referring to a model-based classification, the mixture distribution approach is understood. In contrast, we revive the hard-classification model-based approach developed by Banfield and Raftery (1993) for which K-means is equivalent to the maximum likelihood (ML) estimation. The next-generation K-means algorithm does not end after the classification is achieved, but moves forward to answer the following fundamental questions: Are there clusters, how many clusters are there, what are the statistical properties of the estimated means and index sets, what is the distribution of the coefficients in the clusterwise regression, and how to classify multilevel data? The statistical model-based approach for the K-means algorithm is the key, because it allows statistical simulations and studying the properties of classification following the track of the classical statistics. This paper illustrates the application of the ML classification to testing the no-clusters hypothesis, to studying various methods for selection of the number of clusters using simulations, robust clustering using Laplace distribution, studying properties of the coefficients in clusterwise regression, and finally to multilevel data by marrying the variance components model with K-means.

Indexed as

clusterwise regressionhard classificationK‐mediansmaximum likelihoodmultilevel datarobust clustering, SigClust

Identifiers

PMID30073045
PMCPMC6062903

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.