Evidence map›Paper›PMID 30072833›Full record

ArticleIndian journal of clinical biochemistry : IJCB2018

The Effect of Newly Synthesized Heterosteroids on miRNA34a, 98, and 214 Expression Levels in MCF-7 Breast Cancer Cells.

Shaymaa M M Yahya, Gamal A Elmegeed, Mervat S Mohamed, Rafat M Mohareb, Mervat M Abd-Elhalim, Ghada H Elsayed

Open access · bronzeAbstract read
In one paragraph

Article in Indian journal of clinical biochemistry : IJCB, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact, top 92% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Shaymaa M M Yahya1Hormones Department, National Research Centre, Dokki, Giza, 12622 Egypt.
Gamal A Elmegeed1Hormones Department, National Research Centre, Dokki, Giza, 12622 Egypt.
Mervat S Mohamed2Chemistry Department, Faculty of Science, Cairo University, Cairo, Egypt.
Rafat M Mohareb2Chemistry Department, Faculty of Science, Cairo University, Cairo, Egypt.
Mervat M Abd-Elhalim1Hormones Department, National Research Centre, Dokki, Giza, 12622 Egypt.
Ghada H Elsayed1Hormones Department, National Research Centre, Dokki, Giza, 12622 Egypt.
National Research Centre · EGCairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hybrid anticancer drugs have emerged as great therapeutic options that can effectively overcome most obstacles facing conventional anticancer drugs. miRNAs are considered as class of non-coding RNAs that can negatively regulate protein coding gene expression. miRNA expression is commonly altered in cancer cells. The current work aimed to test the effect of new pro-apoptotic heterosteroids on some drug resistance related miRNAs expression levels (miRNA34a, 98, and 214) in MCF-7 breast cancer cells. After cell treatment with these compounds

Indexed as

Apoptotic genesBreast cancerCytotoxicitymiR-214miR-34amiR-98Steroids

Identifiers

PMID30072833
PMCPMC6052734
OpenAlexW2739080381

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.