Evidence map›Paper›PMID 30072804›Full record

ReviewPediatric research2018

Deformation imaging and rotational mechanics in neonates: a guide to image acquisition, measurement, interpretation, and reference values.

Afif El-Khuffash, Ulf Schubert, Philip T Levy, Eirik Nestaas, Willem P de Boode, European Special Interest Group ‘Neonatologist Performed Echocardiography’ (NPE)

Open access · bronzeAbstract readReview
In one paragraph

Review in Pediatric research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 91 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Patent ductus arteriosus shunt elimination results in a reduction in adverse outcomes: a post hoc analysis of the PDA RCT cohort.Journal of perinatology : official journal of the California Perinatal Association · 2021
    Trial
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Article
  11. Review
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  15. Observational
  16. Characteristics and outcomes of preterm infants with early pulmonary hypertension.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Observational
  17. Article
  18. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 5 countries.

Afif El-KhuffashDepartment of Neonatology, The Rotunda Hospital, Dublin, Ireland.
Ulf SchubertDepartment of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
Philip T LevyDepartment of Pediatrics, Washington University School of Medicine, Saint Louis, MO, USA.
Eirik NestaasInstitute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.
Willem P de BoodeDepartment of Neonatology, Radboud University Medical Center, Radboud Institute for Health Sciences, Amalia Children's Hospital, Nijmegen, The Netherlands. willem.deboode@radboudumc.nl.
European Special Interest Group ‘Neonatologist Performed Echocardiography’ (NPE)
Royal College of Surgeons in Ireland · IEOslo University Hospital · NORadboud University Nijmegen · NLUniversity of Oslo · NOWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Advances in neonatal cardiac imaging permit a more comprehensive assessment of myocardial performance in neonates that could not be previously obtained with conventional imaging. Myocardial deformation analysis is an emerging quantitative echocardiographic technique to characterize global and regional ventricular function in neonates. Cardiac strain is a measure of tissue deformation and strain rate is the rate at which deformation occurs. These measurements are obtained in neonates using tissue Doppler imaging (TDI) or two-dimensional speckle tracking echocardiography (STE). There is an expanding body of literature describing longitudinal reference ranges and maturational patterns of strain values in term and preterm infants. A thorough understanding of deformation principles, the technical aspects, and clinical applicability is a prerequisite for its routine clinical use in neonates. This review explains the fundamental concepts of deformation imaging in the term and preterm population, describes in a comparative manner the two major deformation imaging methods, provides a practical guide to the acquisition and interpretation of data, and discusses their recognized and developing clinical applications in neonates.

Indexed as

EchocardiographyHeartHumansImage Interpretation, Computer-AssistedImage Processing, Computer-AssistedInfant, NewbornInfant, Newborn, DiseasesInfant, PrematureMyocardiumReference ValuesReproducibility of ResultsSoftwareUltrasonography, DopplerVentricular Dysfunction, Left

Identifiers

PMID30072804
PMCPMC6257225
OpenAlexW2887304267

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.