ArticleThe American journal of gastroenterology2018
Risk of Metachronous Advanced Neoplasia in Patients With Multiple Diminutive Adenomas.
Article in The American journal of gastroenterology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.
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Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Computer-aided detection with or without mucosal-exposure devices in colonoscopy: a systematic review and meta-analysis with trial sequential analysis.Surgical endoscopy · 2026Pooled it
- Systematic review: risk prediction models for metachronous advanced colorectal neoplasia after polypectomy.Journal of gastroenterology and hepatology · 2024Pooled it
- Higher Adenoma Detection Rates at Screening Associated With Lower Long-Term Colorectal Cancer Incidence and Mortality.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2022Trial
- A Cohort Study on Systemic Immune-Inflammation Index and Its Longitudinal Change in Relation to Colorectal Adenoma Recurrence.Journal of inflammation research · 2026Article
- Predictors of metachronous advanced colorectal adenoma after polypectomy.Journal of the Chinese Medical Association : JCMA · 2025Article
- Artificial intelligence for colorectal neoplasia detection during colonoscopy: a systematic review and meta-analysis of randomized clinical trials.EClinicalMedicine · 2023Article
- Clinical outcomes of colonoscopic polypectomy with strategic surveillance colonoscopies in patients with 10 or more polyps.Scientific reports · 2023Observational
- Korean Guidelines for Postpolypectomy Colonoscopic Surveillance: 2022 revised edition.Intestinal research · 2023Review
- Korean guidelines for postpolypectomy colonoscopic surveillance: 2022 revised edition.Clinical endoscopy · 2022Review
- [Korean Guidelines for Postpolypectomy Colonoscopic Surveillance: 2022 Revised Edition].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2022Review
- Does computer-aided diagnostic endoscopy improve the detection of commonly missed polyps? A meta-analysis.Clinical endoscopy · 2022Article
- Early-Onset Colorectal Cancer Is Associated with a Lower Risk of Metachronous Advanced Neoplasia than Traditional-Onset Colorectal Cancer.Digestive diseases and sciences · 2022Article
- Risk of adenoma recurrence after polypectomy in patients younger than 50 years vs. 50 years old and over with diminutive or small adenomas.Frontiers in oncology · 2022Article
- Prevalence of Metachronous Advanced Colorectal Neoplasia in Black and White Patients at a Safety Net Hospital.Gastro hep advances · 2022Article
- Does Colon Polyp Surveillance Improve Patient Outcomes?Gastroenterology · 2020Article
- UEG Week 2019 Poster Presentations.United European gastroenterology journal · 2019Article
- Association of small versus diminutive adenomas and the risk for metachronous advanced adenomas: data from the New Hampshire Colonoscopy Registry.Gastrointestinal endoscopy · 2019Article
- Update in Surveillance Recommendations in Individuals With Conventional Adenomas.Current treatment options in gastroenterology · 2019Review
- Thinking Big About Small Adenomas: Moving Toward "Precision Surveillance".The American journal of gastroenterology · 2018Article
- Appendiceal Tumors: A Narrative Review.In vivo (Athens, Greece)Review
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesIndividuals with advanced adenomas or three or more adenomas have a higher risk of metachronous advanced neoplasia (AN) and are recommended to undergo surveillance colonoscopy at shorter intervals. However, it is questionable whether patients with multiple (three or more) non-advanced diminutive adenomas should be considered as high-risk.
methodsWe analyzed 5482 patients diagnosed with one or more adenomas during their first colonoscopy screening and who underwent a follow-up colonoscopy. Patients were categorized into four groups based on adenoma characteristics at baseline: Group 1, 1-2 non-advanced adenomas; Group 2, ≥3 non-advanced, diminutive (1 to 5 mm) adenomas; Group 3, ≥3 non-advanced, small (6-9 mm) adenomas; and Group 4, advanced adenomas.
resultsDuring a median follow-up of 38 months, the incidence of metachronous AN at surveillance colonoscopy was 5.6%. The incidence of AN was 3.9% in group 1, 5.9% in group 2, 10.6% in group 3, and 22.1% in group 4. The adjusted hazard ratios (HRs) [95% confidence intervals (CIs)] for metachronous AN between group 2, group 3, and group 4, and low risk group 1 were 1.71 (0.99-2.94), 2.76 (1.72-4.44), and 5.23 (3.57-7.68), respectively. Compared with group 4, the adjusted HRs (95% CIs) for group 1, group 2, and group 3 were 0.19 (0.13-0.28), 0.32 (0.18-0.59), and 0.52 (0.31-0.89), respectively.
conclusionsWe found that patients with three or more non-advanced diminutive adenomas had a borderline increased risk of metachronous AN compared with patients with low risk adenomas.
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