Evidence map›Paper›PMID 30072580›Full record

ArticleMolecular & cellular proteomics : MCP2019

Modification of Crocodile Spermatozoa Refutes the Tenet That Post-testicular Sperm Maturation Is Restricted To Mammals.

Brett Nixon, Stephen D Johnston, David A Skerrett-Byrne, Amanda L Anderson, Simone J Stanger, Elizabeth G Bromfield, Jacinta H Martin, Philip M Hansbro, Matthew D Dun

Open access · hybridAbstract read
In one paragraph

Article in Molecular & cellular proteomics : MCP, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 46 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. FromiScience · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Post-ejaculatory modifications to sperm (PEMS).Biological reviews of the Cambridge Philosophical Society · 2020
    Review
  15. Article
  16. Reproductive Proteomics Comes of Age.Molecular & cellular proteomics : MCP · 2019
    Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Brett NixonFrom the ‡Priority Research Centre for Reproductive Science, School of Environmental and Life Sciences, The University of Newcastle, Callaghan, NSW 2308, Australia;; Hunter Medical Research Institute, New Lambton Heights, NSW 2305, Australia;. Electronic address: Brett.Nixon@newcastle.edu.au.
Stephen D JohnstonSchool of Agriculture and Food Science, The University of Queensland, Gatton, QLD 4343, Australia.
David A Skerrett-ByrneHunter Medical Research Institute, New Lambton Heights, NSW 2305, Australia.
Amanda L AndersonFrom the ‡Priority Research Centre for Reproductive Science, School of Environmental and Life Sciences, The University of Newcastle, Callaghan, NSW 2308, Australia.
Simone J StangerFrom the ‡Priority Research Centre for Reproductive Science, School of Environmental and Life Sciences, The University of Newcastle, Callaghan, NSW 2308, Australia.
Elizabeth G BromfieldFrom the ‡Priority Research Centre for Reproductive Science, School of Environmental and Life Sciences, The University of Newcastle, Callaghan, NSW 2308, Australia;; Hunter Medical Research Institute, New Lambton Heights, NSW 2305, Australia.
Jacinta H MartinFrom the ‡Priority Research Centre for Reproductive Science, School of Environmental and Life Sciences, The University of Newcastle, Callaghan, NSW 2308, Australia;; Hunter Medical Research Institute, New Lambton Heights, NSW 2305, Australia.
Philip M HansbroHunter Medical Research Institute, New Lambton Heights, NSW 2305, Australia;; Priority Research Centre for Healthy Lungs, Faculty of Health and Medicine, The University of Newcastle, Newcastle, NSW 2308, Australia.
Matthew D DunHunter Medical Research Institute, New Lambton Heights, NSW 2305, Australia;; Priority Research Centre for Cancer Research, Innovation and Translation, School of Biomedical Sciences and Pharmacy, Faculty of Health and Medicine, The University of Newcastle, Callaghan, NSW 2308, Australia.
Hunter Medical Research Institute · AUUniversity of Newcastle Australia · AUUniversity of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Competition to achieve paternity has contributed to the development of a multitude of elaborate male reproductive strategies. In one of the most well-studied examples, the spermatozoa of all mammalian species must undergo a series of physiological changes, termed capacitation, in the female reproductive tract before realizing their potential to fertilize an ovum. However, the evolutionary origin and adaptive advantage afforded by capacitation remains obscure. Here, we report the use of comparative and quantitative proteomics to explore the biological significance of capacitation in an ancient reptilian species, the Australian saltwater crocodile (

Indexed as

Alligators and CrocodilesAnimalsCarbonyl Cyanide m-Chlorophenyl HydrazoneGene OntologyMaleMammalsMolecular Sequence AnnotationPeptidesPhosphopeptidesPhosphorylationProteomeProteomicsReproducibility of ResultsSpermatozoaSperm CapacitationSperm MaturationCarbonyl Cyanide m-Chlorophenyl HydrazonePeptidesPhosphopeptidesProteomecapacitationCell biology*crocodileCrocodylus porosusDevelopmental biology*PhosphoproteomePhosphorylationPhysiology*Post-translational modifications*Protein Identification*Protein Modification*Serine/Threonine Kinases*Signal Transduction*sperm

Identifiers

PMID30072580
PMCPMC6427239
OpenAlexW2886372704

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.