Evidence map›Paper›PMID 30072421›Full record

ArticleMolecular systems biology2018

Metabolic oscillations on the circadian time scale in

Guillaume Rey, Nikolay B Milev, Utham K Valekunja, Ratnasekhar Ch, Sandipan Ray, Mariana Silva Dos Santos, Andras D Nagy, Robin Antrobus, James I MacRae, Akhilesh B Reddy

Open access · goldAbstract read
In one paragraph

Article in Molecular systems biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Article
  3. Autonomous Redox Rhythms and Their Coupling to the Circadian Clock.Advances in experimental medicine and biology · 2026
    Review
  4. The redox rhythm gates immune-induced cell death distinctly from the genetic clock.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. Article
  6. Evidence for ~12-h ultradian gene programs in humans.Npj biological timing and sleep · 2024
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Circadian and Sleep Metabolomics Across Species.Journal of molecular biology · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Guillaume ReyThe Francis Crick Institute, London, UK guiomrey@gmail.com areddy@cantab.net.ORCID 0000-0001-7664-7052
Nikolay B MilevThe Francis Crick Institute, London, UK.
Utham K ValekunjaThe Francis Crick Institute, London, UK.
Ratnasekhar ChThe Francis Crick Institute, London, UK.
Sandipan RayThe Francis Crick Institute, London, UK.
Mariana Silva Dos SantosThe Francis Crick Institute, London, UK.ORCID 0000-0003-2404-8490
Andras D NagyThe Francis Crick Institute, London, UK.ORCID 0000-0003-1759-4039
Robin AntrobusCambridge Institute for Medical Research (CIMR), Wellcome Trust/MRC Building, Addenbrooke's Hospital, Cambridge, UK.
James I MacRaeThe Francis Crick Institute, London, UK.
Akhilesh B ReddyThe Francis Crick Institute, London, UK guiomrey@gmail.com areddy@cantab.net.ORCID 0000-0003-3328-1470
The Francis Crick Institute · GBAddenbrooke's Hospital · GB

Funding

Cancer Research UK FC001534Medical Research Council FC001534Wellcome TrustWellcome Trust 100333/Z/12/ZWellcome Trust FC001534
6 · The paper itself

Abstract

Circadian rhythms are cell-autonomous biological oscillations with a period of about 24 h. Current models propose that transcriptional feedback loops are the primary mechanism for the generation of circadian oscillations. Within this framework,

Indexed as

AnimalsBiological ClocksCircadian RhythmDrosophila melanogasterMetabolomicsProteomeTranscriptomeProteomecircadianclocksmetabolomicsproteomicstranscriptomics

Identifiers

PMID30072421
PMCPMC6078164
OpenAlexW2887644718

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.