ArticleDiabetes care2018
Adverse Childhood Experiences and the Risk of Diabetes: Examining the Roles of Depressive Symptoms and Cardiometabolic Dysregulations in the Whitehall II Cohort Study.
Article in Diabetes care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
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Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 69 citations in OpenAlex.
- Dimensions of early life adversity and cardiometabolic health in adulthood: A systematic review and meta-analysis.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2026Pooled it
- Adverse childhood experiences and well-being in middle-aged men in South Korea: mediating role of andropause symptoms.Health and quality of life outcomes · 2026Article
- Spironolactone ameliorates the endothelial dysfunction induced by visceral adipose tissue in obese female mice exposed to early life stress.Journal of applied physiology (Bethesda, Md. : 1985) · 2026Article
- Adverse Life Events Across the Life Course and the Risk of New-Onset Cardiovascular-Kidney-Metabolic Multimorbidity in Middle-Aged and Older Adults: Longitudinal Evidence From CHARLS.Journal of the American Heart Association · 2025Article
- Childhood Adversity and Cardiovascular Disease; Current Knowledge and Future Directions.Current cardiology reports · 2025Review
- Adverse childhood experiences and prevalence of type 2 diabetes in a nationwide study of women.European journal of public health · 2025Article
- Article
- Associations of adverse childhood experiences with midlife cardiovascular health in women.American journal of preventive cardiology · 2025Article
- Perceived criticism and depressive symptoms among adults aged 50 years and older: a 17-year population-based cohort study.Translational psychiatry · 2025Article
- Adverse childhood experiences and hypertension: examining the roles of depressive symptoms and cardiometabolic dysregulations based on CHARLS data.Frontiers in public health · 2025Article
- Childhood maltreatment, adulthood obesity and incident type 2 diabetes: a retrospective cohort study using UK Biobank.International journal of obesity (2005) · 2025Article
- Associations of adverse childhood experiences with blood pressure among early adolescents in the United States.American journal of preventive cardiology · 2024Article
- Pathophysiology and Treatment of Prediabetes and Type 2 Diabetes in Youth.Diabetes care · 2024Review
- Adverse childhood experiences and adult disease: Examining mediating pathways in the Hispanic Community Health Study/Study of Latinos Sociocultural Ancillary Study.Health psychology : official journal of the Division of Health Psychology, American Psychological Association · 2024Article
- The association between adverse childhood experiences and adult cardiac function in the UK Biobank.European heart journal. Imaging methods and practice · 2024Article
- Social Determinants of Health in Cardio-Oncology: Multi-Level Strategies to Overcome Disparities in Care:JACC. CardioOncology · 2024Review
- Childhood maltreatment and risk of endocrine diseases: an exploration of mediating pathways using sequential mediation analysis.BMC medicine · 2024Article
- Treatment of type 2 diabetes and stress using neuro-emotional technique: case report.Frontiers in endocrinology · 2024Article
- Adverse childhood experiences of Korean mothers with young children: a latent class analysis.European journal of psychotraumatology · 2024Article
- Biopsychosocial factors in oral and systemic diseases: a scoping review.Frontiers in oral health · 2024Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
Abstract
objectiveAdverse childhood experiences (ACEs) are associated with an increased risk of diabetes in adulthood. However, the potential mediating roles of depression and cardiometabolic dysregulations in this association are not clear. RESEARCH DESIGN AND
methodsProspective data were from the Whitehall II cohort study, with the phase 5 assessment (1997-1999) serving as baseline (
resultsACEs were associated with an increased likelihood of diabetes, with every addition of ACE associated with an ∼11% increase in odds of diabetes (odds ratio 1.11 [95% CI 1.00, 1.24],
conclusionsThis study provides further evidence of the detrimental psychological and physiological effects of ACEs and suggests that depression and cardiometabolic dysregulations may be pathways linking ACEs with diabetes in adulthood.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.