Evidence map›Paper›PMID 30072381›Full record

ArticleThe Journal of biological chemistry2018

The Ras-like GTPase Rem2 is a potent inhibitor of calcium/calmodulin-dependent kinase II activity.

Leandro Royer, Josiah J Herzog, Katelyn Kenny, Boriana Tzvetkova, Jesse C Cochrane, Michael T Marr, Suzanne Paradis

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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  4. Article
  5. Review
  6. Article
  7. Experience-Dependent Development of Dendritic Arbors in Mouse Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Leandro RoyerFrom the Department of Biology.
Josiah J HerzogFrom the Department of Biology.
Katelyn KennyFrom the Department of Biology.
Boriana TzvetkovaFrom the Department of Biology.
Jesse C CochraneDepartment of Molecular Biology and Genetics, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114.
Michael T MarrFrom the Department of Biology, mmarr@brandeis.edu.
Suzanne ParadisFrom the Department of Biology, paradis@brandeis.edu.
Brandeis University · USHarvard University · US

Funding

Semaphorin-Dependent GABAergic Synapse Formation: A Novel Approach to Increasing Inhibition in the Intact BrainR01NS065856 · NINDS · BRANDEIS UNIVERSITY · PI PARADIS, SUZANNE · 2010 to 2024
$5.4M
Quantitative Biology: a Graduate Curriculum Linking the Physical and Biomedical ST32EB009419 · NIBIB · BRANDEIS UNIVERSITY · PI GELLES, JEFF, KONDEV, JANE · 2009 to 2018
$2.8M
FOXO Regulon and Translation ControlR01GM117034 · NIGMS · BRANDEIS UNIVERSITY · PI MARR, MICHAEL THOMAS · 2016 to 2019
$1.3M
Defining the mechanism of CaMKII inhibition by the non-canonical GTPase Rem2R21NS102661 · NINDS · BRANDEIS UNIVERSITY · PI MARR, MICHAEL THOMAS, PARADIS, SUZANNE · 2017 to 2018
$445k
NIGMS NIH HHS R01 GM117034NINDS NIH HHS R01 NS065856NINDS NIH HHS R21 NS102661
6 · The paper itself

Abstract

Ca

Indexed as

AnimalsCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2Cells, CulturedHEK293 CellsHippocampusHomeostasisHumansLearningLong-Term PotentiationMemoryMiceMonomeric GTP-Binding ProteinsNeuronal PlasticityNeuronsPhosphorylationCalciumCalcium-Calmodulin-Dependent Protein Kinase Type 2Monomeric GTP-Binding ProteinsREM2 protein, humanRem2 protein, mouseautophosphorylationCa2+/calmodulin-dependent protein kinase II (CaMKII)calciumGTPaseinhibitorphosphorylationRem2RGK family

Identifiers

PMID30072381
PMCPMC6153278
OpenAlexW2887044863

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.