Evidence map›Paper›PMID 30071888›Full record

ArticleBMC research notes2018

The correlation of age and body mass index with the level of both protease MMP3 and anti-protease TIMP-1 among Indonesian patients with chronic obstructive pulmonary disease: a preliminary findings.

Mulyadi, Sunnati, Mulkan Azhary, Faisal Yunus, Fariz Nurwidya

Open access · goldAbstract read
In one paragraph

Article in BMC research notes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

MulyadiDepartment of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia.
SunnatiDepartment of Periodontology, Faculty of Dentistry, Universitas Syiah Kuala, Banda Aceh, Indonesia.
Mulkan AzharyDepartment of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia.
Faisal YunusDepartment of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan Hospital, Jalan Persahabatan Raya No.1, Rawamangun, Jakarta, 13230, Indonesia.
Fariz NurwidyaDepartment of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Indonesia, Persahabatan Hospital, Jalan Persahabatan Raya No.1, Rawamangun, Jakarta, 13230, Indonesia. fariz.nurwidya@gmail.com.ORCID http://orcid.org/0000-0002-8379-9510
Universitas Syiah Kuala · IDUniversity of Indonesia · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIndividuals with chronic obstructive pulmonary disease (COPD) are usually > 50 years of age and have a low body mass index (BMI). An imbalance between matrix metalloproteinases (MMPs), including MMP-3, and tissue inhibitor of metalloproteinase 1 (TIMP-1), play a role in tissue degradation of lung extracellular matrix among COPD individuals. The purpose of the present study was to correlate age and/or BMI with salivary levels of MMP-3 and TIMP-1 among Indonesian subjects with COPD.

resultsThirty COPD patients were recruited to undergo thorough physical assessment and saliva collection for evaluating TIMP-1 and MMP-3 levels using commercially available kits enzyme-linked immunosorbent assay method. The mean (standard deviation) participant age and BMI were 60.5 (8.13) years, and 23.1 (4.75) kg/m

Indexed as

Body Mass IndexAdaptor Proteins, Signal TransducingAgedFemaleHumansIndonesiaMaleMatrix Metalloproteinase 3Matrix Metalloproteinase 9Middle AgedPulmonary Disease, Chronic ObstructiveTissue Inhibitor of Metalloproteinase-1Adaptor Proteins, Signal TransducingMatrix Metalloproteinase 3Matrix Metalloproteinase 9MMP3 protein, humanTIMP1 protein, humanTissue Inhibitor of Metalloproteinase-1AgeBMISalivary MMP-3Salivary TIMP-1

Identifiers

PMID30071888
PMCPMC6071396
OpenAlexW2886149501

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.