ReviewCritical care (London, England)2018
Improving glycemic control in critically ill patients: personalized care to mimic the endocrine pancreas.
Review in Critical care (London, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 51 citations in OpenAlex.
- Bolus versus continuous insulin infusion in immediate postoperative blood glucose control in liver transplantation: pragmatic clinical trial.Einstein (Sao Paulo, Brazil) · 2022Trial
- Diabetes Management Strategies in Intensive Care Settings.The Medical clinics of North America · 2026Review
- Estimating Enhanced Endogenous Glucose Production in Intensive Care Unit Patients with Severe Insulin Resistance.Journal of diabetes science and technology · 2022Article
- Two Decades of Research in Artificial Pancreas: Insights from a Bibliometric Analysis.Journal of diabetes science and technology · 2022Article
- Preadmission Insulin-Treated Type 2 Diabetes Mellitus Patients Had Increased Mortality in Intensive Care Units.Diabetes, metabolic syndrome and obesity : targets and therapy · 2022Article
- Practice of hyperglycaemia control in intensive care units of the Military Hospital, Sudan-Needs of a protocol.PloS one · 2022Article
- Stochastic Modelling of Respiratory System Elastance for Mechanically Ventilated Respiratory Failure Patients.Annals of biomedical engineering · 2021Observational
- Insulin sensitivity in critically ill patients: are women more insulin resistant?Annals of intensive care · 2021Article
- Risk-Based Care: Let's Think Outside the Box.Frontiers in medicine · 2021Article
- Algorithm Maxima for Intravenous Insulin Infusion.Diabetes technology & therapeutics · 2020Article
- Issues for the management of people with diabetes and COVID-19 in ICU.Cardiovascular diabetology · 2020Review
- Accuracy of Blood Glucose Measurement and Blood Glucose Targets.Journal of diabetes science and technology · 2020Review
- Risk and reward: extending stochastic glycaemic control intervals to reduce workload.Biomedical engineering online · 2020Article
- Association Between Blood Glucose Within 24 Hours After Intensive Care Unit Admission and Prognosis: A Retrospective Cohort Study.Diabetes, metabolic syndrome and obesity : targets and therapy · 2020Article
- Assessment of Glycemic Control Protocol (STAR) Through Compliance Analysis Amongst Malaysian ICU Patients.Medical devices (Auckland, N.Z.) · 2020Article
- Glucose control in the ICU.Current opinion in anaesthesiology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 10 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is considerable physiological and clinical evidence of harm and increased risk of death associated with dysglycemia in critical care. However, glycemic control (GC) currently leads to increased hypoglycemia, independently associated with a greater risk of death. Indeed, recent evidence suggests GC is difficult to safely and effectively achieve for all patients. In this review, leading experts in the field discuss this evidence and relevant data in diabetology, including the artificial pancreas, and suggest how safe, effective GC can be achieved in critically ill patients in ways seeking to mimic normal islet cell function. The review is structured around the specific clinical hurdles of: understanding the patient's metabolic state; designing GC to fit clinical practice, safety, efficacy, and workload; and the need for standardized metrics. These aspects are addressed by reviewing relevant recent advances in science and technology. Finally, we provide a set of concise recommendations to advance the safety, quality, consistency, and clinical uptake of GC in critical care. This review thus presents a roadmap toward better, more personalized metabolic care and improved patient outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.