Evidence map›Paper›PMID 30071698›Full record

ArticlePharmaceutics2018

Tannic Acid-Lung Fluid Assemblies Promote Interaction and Delivery of Drugs to Lung Cancer Cells.

Elham Hatami, Prashanth K B Nagesh, Pallabita Chowdhury, Subhash C Chauhan, Meena Jaggi, Amali E Samarasinghe, Murali M Yallapu

Abstract read
In one paragraph

Article in Pharmaceutics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. ACS applied bio materials · 2022
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Ormeloxifene nanotherapy for cervical cancer treatment.International journal of nanomedicine · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elham HatamiDepartment of Pharmaceutical Sciences and Center for Cancer Research, University of Tennessee Health Science Center, Memphis, TN 38103, USA. ehatami@uthsc.edu.ORCID 0000-0001-6776-4003
Prashanth K B NageshDepartment of Pharmaceutical Sciences and Center for Cancer Research, University of Tennessee Health Science Center, Memphis, TN 38103, USA. pbhusett@uthsc.edu.
Pallabita ChowdhuryDepartment of Pharmaceutical Sciences and Center for Cancer Research, University of Tennessee Health Science Center, Memphis, TN 38103, USA. pchowdhu@uthsc.edu.
Subhash C ChauhanDepartment of Pharmaceutical Sciences and Center for Cancer Research, University of Tennessee Health Science Center, Memphis, TN 38103, USA. schauha1@uthsc.edu.
Meena JaggiDepartment of Pharmaceutical Sciences and Center for Cancer Research, University of Tennessee Health Science Center, Memphis, TN 38103, USA. mjaggi@uthsc.edu.
Amali E SamarasingheDepartment of Paediatrics, University of Tennessee Health Science Center, Memphis, TN 38103, USA. asamaras@uthsc.edu.ORCID 0000-0002-3104-2823
Murali M YallapuDepartment of Pharmaceutical Sciences and Center for Cancer Research, University of Tennessee Health Science Center, Memphis, TN 38103, USA. myallapu@uthsc.edu.

Funding

Targeted Nano-Chemosensitization of Breast CancersR15CA213232 · NCI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI KUMAR, SANTOSH · 2017 to 2017
$440k
NCI NIH HHS R15 CA213232
6 · The paper itself

Abstract

Lung cancer (LC) is one of the leading causes of death in both men and women in the United States. Tannic acid (TA), a water-soluble polyphenol, exhibits a wide range of biological activities. TA has received much attention as a promising compound in the biomaterial and drug delivery fields. Lung fluid (LF) is a major barrier for distribution of drugs to the lungs. Therefore, the purpose of this study was to examine TA interaction with LF for effective delivery of anti-cancer drug molecules via pulmonary delivery. The extent of adsorption of LF proteins by TA was revealed by fluorescence quenching in fluorescence spectroscopy. The presence of LF in TA-LF complexes was noticed by the presence of protein peaks at 1653 cm

Indexed as

cancer therapeuticslung cancerlung fluidprotein coronatannic acid

Identifiers

PMID30071698
PMCPMC6161105

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.