Evidence map›Paper›PMID 30071651›Full record

ArticleGenes2018

Faruk Hadziselimovic, Gieri Cathomas, Gilvydas Verkauskas, Darius Dasevicius, Michael B Stadler

Open access · goldAbstract read
In one paragraph

Article in Genes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. PRDM12 in Health and Diseases.International journal of molecular sciences · 2021
    Review
  5. Article
  6. Advocating hormonal treatment to prevent adult in-fertility in patients diagnosed with congenital un-descended testes.International braz j urol : official journal of the Brazilian Society of Urology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Faruk HadziselimovicCryptorchidism Research Institute, Kindermedizinisches Zentrum Liestal, Bahnhofplatz 11, CH-4410 Liestal, Switzerland. liestal@kindermedizin-zentrum.ch.
Gieri CathomasDepartment of Pathology Kantonspital Liestal, 4410 Liestal, Switzerland. gieri.cathomas@ksbl.ch.
Gilvydas VerkauskasChildren's Surgery Centre, Faculty of Medicine, University of Vilnius, 01513 Vilnius, Lithuania. gilvydas.verkauskas@vuvl.lt.
Darius DaseviciusInstitute for Pathology, National Centre of Pathology, Affiliate of Vilnius University Hospital Santariskiu Klinikos, 08406 Vilnius, Lithuania. darius.dasevicius@vpc.lt.
Michael B StadlerSwiss Institute of Bioinformatics, 4058 Basel, Switzerland. michael.stadler@fmi.ch.
Friedrich Miescher Institute · CHKantonsspital Baselland · CHVilnius University Hospital Santariskiu Klinikos · LTVilnius University of Applied Sciences · LT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is a correlation between cryptorchidism and an increased risk of testicular cancer and infertility. During orchidopexy, testicular biopsies are performed to confirm the presence of type A dark (Ad) spermatogonia, which are a marker for low infertility risk (LIR). The Ad spermatogonia are absent in high infertility risk (HIR) patients, who are treated with a gonadotropin-releasing hormone agonist (GnRHa) to significantly lower the risk of infertility. Despite its prevalence, little is known about the molecular events involved in cryptorchidism. Previously, we compared the transcriptomes of LIR versus HIR patients treated with and without hormones. Here, we interpreted data regarding members of the positive regulatory domain-containing (

Indexed as

cryptorchidismGnRHainfertilityPRDMRNA-sequencing

Identifiers

PMID30071651
PMCPMC6116052
OpenAlexW2886193527

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.