Evidence map›Paper›PMID 30071572›Full record

ArticleNeurospine2018

Current Status of the Use of Salvaged Blood in Metastatic Spine Tumour Surgery.

Naresh Kumar, Nivetha Ravikumar, Joel Yong Hao Tan, Kutbuddin Akbary, Ravish Shammi Patel, Rajesh Kannan

Abstract read
In one paragraph

Article in Neurospine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. [Effect of intraoperative blood salvage autotransfusion on the prognosis of patients after carotid body tumor resection].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Blood loss in totalJournal of spine surgery (Hong Kong) · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Naresh KumarDepartment of Orthopaedic Surgery, National University Health System, Singapore.
Nivetha RavikumarDepartment of Orthopaedic Surgery, National University Health System, Singapore.
Joel Yong Hao TanDepartment of Orthopaedic Surgery, National University Health System, Singapore.
Kutbuddin AkbaryDepartment of Orthopaedic Surgery, National University Health System, Singapore.
Ravish Shammi PatelDepartment of Orthopaedic Surgery, National University Health System, Singapore.
Rajesh KannanDepartment of Anaesthesiology, National University Hospital, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To review the current status of salvaged blood transfusion (SBT) in metastatic spine tumour surgery (MSTS), with regard to its safety and efficacy, contraindications, and adverse effects. We also aimed to establish that the safety and adverse event profile of SBT is comparable and at least equal to that of allogeneic blood transfusion. MEDLINE and Scopus were used to search for relevant articles, based on keywords such as "cancer surgery," "salvaged blood," and "circulating tumor cells." We found 159 articles, of which 55 were relevant; 20 of those were excluded because they used other blood conservation techniques in addition to cell salvage. Five articles were manually selected from reference lists. In total, 40 articles were reviewed. There is sufficient evidence of the clinical safety of using salvaged blood in oncological surgery. SBT decreases the risk of postoperative infections and tumour recurrence. However, there are some limitations regarding its clinical applications, as it cannot be employed in cases of sepsis. In this review, we established that earlier studies supported the use of salvaged blood from a cell saver in conjunction with a leukocyte depletion filter (LDF). Furthermore, we highlight the recent emergence of sufficient evidence supporting the use of intraoperative cell salvage without an LDF in MSTS.

Indexed as

Autologous salvaged bloodCancer surgeryCirculating neoplastic cellsIntraoperative cell salvageMetastatic cancer surgeryMetastatic spine tumour surgery

Identifiers

PMID30071572
PMCPMC6226127

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.