Evidence map›Paper›PMID 30071221›Full record

ArticleInternational journal of biological macromolecules2018

Sialic acid involves in the interaction between ovomucin and hemagglutinin and influences the antiviral activity of ovomucin.

Qi Xu, Yuanyuan Shan, Ning Wang, Yaping Liu, Maojie Zhang, Meihu Ma

Abstract read
In one paragraph

Article in International journal of biological macromolecules, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Sialic acid: an attractive biomarker with promising biomedical applications.Asian biomedicine : research, reviews and news · 2022
    Review
  5. Article
  6. Review
  7. SialylatedJournal of applied glycoscience · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Qi XuCollege of Food Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, People's Republic of China.
Yuanyuan ShanCollege of Food Science and Engineering, Northwest A&F University, Yangling 712100, People's Republic of China.
Ning WangCollege of Food Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, People's Republic of China.
Yaping LiuCollege of Food Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, People's Republic of China.
Maojie ZhangCollege of Food Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, People's Republic of China.
Meihu MaCollege of Food Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, People's Republic of China. Electronic address: mameihuhn@163.com.
Huazhong Agricultural University · CNNorthwest A&F University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovomucin (OVM) plays an important role in inhibiting infection of various pathogens. However, this bioactivity mechanism is not much known. Here, the role of sialic acid in OVM anti-virus activity has been studied by ELISA with lectin or ligand. Structural changes of OVM after removing sialic acid were analyzed by circular dichroism and fluorescence spectroscopy. OVM could be binding to the hemagglutinin (HA) of avian influenza viruses H

Indexed as

Antiviral AgentsHemagglutininsInfluenza A Virus, H1N1 SubtypeInfluenza A Virus, H5N1 SubtypeN-Acetylneuraminic AcidOvomucinAntiviral AgentsHemagglutininsN-Acetylneuraminic AcidOvomucinAntiviral mechanismAvian influenza virusGlycosylationOvomucinSialic acid

Identifiers

PMID30071221
PMCPMC7124660
OpenAlexW2887981394

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.