Evidence map›Paper›PMID 30071036›Full record

ArticlePloS one2018

Assessing genetic architecture and signatures of selection of dual purpose Gir cattle populations using genomic information.

Amanda Marchi Maiorano, Daniela Lino Lourenco, Shogo Tsuruta, Alejandra Maria Toro Ospina, Nedenia Bonvino Stafuzza, Yutaka Masuda, Anibal Eugenio Vercesi Filho, Joslaine Noely Dos Santos Goncalves Cyrillo, Rogério Abdallah Curi, Josineudson Augusto Ii de Vasconcelos Silva

Abstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Research on the Historical Dynamics of Baicheng Oil Chicken Populations.Animals : an open access journal from MDPI · 2025
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  19. Runs of homozygosity and signatures of selection for number of oocytes and embryos in the Gir Indicine cattle.Mammalian genome : official journal of the International Mammalian Genome Society · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Amanda Marchi MaioranoFaculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista "Júlio de Mesquita Filho", Jaboticabal, Sao Paulo, Brazil.ORCID 0000-0002-8496-1591
Daniela Lino LourencoAnimal and Dairy Science, Animal Breeding and Genetics, University of Georgia, Athens, Georgia, United States of America.
Shogo TsurutaAnimal and Dairy Science, Animal Breeding and Genetics, University of Georgia, Athens, Georgia, United States of America.
Alejandra Maria Toro OspinaFaculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista "Júlio de Mesquita Filho", Jaboticabal, Sao Paulo, Brazil.
Nedenia Bonvino StafuzzaFaculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista "Júlio de Mesquita Filho", Jaboticabal, Sao Paulo, Brazil.
Yutaka MasudaAnimal and Dairy Science, Animal Breeding and Genetics, University of Georgia, Athens, Georgia, United States of America.
Anibal Eugenio Vercesi FilhoInstituto de Zootecnia, Nova Odessa, Sao Paulo, Brazil.
Joslaine Noely Dos Santos Goncalves CyrilloInstituto de Zootecnia, Sertãozinho, Sao Paulo, Brazil.
Rogério Abdallah CuriFaculdade de Medicina Veterinária e Zootecnia, Universidade Estadual Paulista "Júlio de Mesquita Filho", Botucatu, Sao Paulo, Brazil.
Josineudson Augusto Ii de Vasconcelos SilvaFaculdade de Medicina Veterinária e Zootecnia, Universidade Estadual Paulista "Júlio de Mesquita Filho", Botucatu, Sao Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gir is one of the main cattle breeds raised in tropical South American countries. Strong artificial selection through its domestication resulted in increased genetic differentiation among the countries in recent years. Over the years, genomic studies in Gir have become more common. However, studies of population structure and signatures of selection in divergent Gir populations are scarce and need more attention to better understand genetic differentiation, gene flow, and genetic distance. Genotypes of 173 animals selected for growth traits and 273 animals selected for milk production were used in this study. Clear genetic differentiation between beef and dairy populations was observed. Different criteria led to genetic divergence and genetic differences in allele frequencies between the two populations. Gene segregation in each population was forced by artificial selection, promoting isolation, and increasing genetic variation between them. Results showed evidence of selective forces in different regions of the genome. A total of 282 genes were detected under selection in the test population based on the fixation index (Fst), integrated haplotype score (iHS), and cross-population extend haplotype homozygosity (XP-EHH) approaches. The QTL mapping identified 35 genes associated with reproduction, milk composition, growth, meat and carcass, health, or body conformation traits. The investigation of genes and pathways showed that quantitative traits associated to fertility, milk production, beef quality, and growth were involved in the process of differentiation of these populations. These results would support further investigations of population structure and differentiation in the Gir breed.

Indexed as

GenomeAnimalsCattleChromosome MappingGenetic VariationGenomicsGenotypeHaplotypesPolymorphism, Single NucleotidePopulation DensityPrincipal Component AnalysisSelection, GeneticSouth America

Identifiers

PMID30071036
PMCPMC6071998

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.