ArticlePLoS biology2018
The importance of being persistent: The first true resident gut symbiont in Drosophila.
Article in PLoS biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Microbial Symbiosis in Lepidoptera: Analyzing the Gut Microbiota for Sustainable Pest Management.Biology · 2025Review
- Cellular and molecular organization of the Drosophila foregut.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Flagellar Genes Are Associated with the Colonization Persistence Phenotype of the Drosophila melanogaster Microbiota.Microbiology spectrum · 2023Article
- Transmission of beneficial yeasts accompanies offspring production inEcology and evolution · 2023Article
- How It All Begins: Bacterial Factors Mediating the Colonization of Invertebrate Hosts by Beneficial Symbionts.Microbiology and molecular biology reviews : MMBR · 2022Review
- Dairy associations for the targeted control of opportunistic Candida.World journal of microbiology & biotechnology · 2021Article
- Metagenomic Survey of the Highly PolyphagousFrontiers in microbiology · 2021Article
- Review
- Gut Bacteria in the Holometabola: A Review of Obligate and Facultative Symbionts.Journal of insect science (Online) · 2020Review
- Drosophila-associated bacteria differentially shape the nutritional requirements of their host during juvenile growth.PLoS biology · 2020Article
- Ecological specificity of the metagenome in a set of lower termite species supports contribution of the microbiome to adaptation of the host.Animal microbiome · 2019Article
- Commensal Gut Bacteria Buffer the Impact of Host Genetic Variants on Drosophila Developmental Traits under Nutritional Stress.iScience · 2019Article
- The Intestine ofMicroorganisms · 2019Review
- Fly foregut and transmission of microbes.Advances in insect physiology · 2019Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the animal kingdom, nutritional mutualism is a perpetual and intimate dialogue carried out between the host and its associated gut community members. This dialogue affects many aspects of the host's development and physiology. Some constituents of the animal gut microbiota can stably reside within the host for years, and such long-term persistence might be a prerequisite for these microbes to assert their beneficial impact. How long-term persistence is established and maintained is an interesting question, and several classic model organisms associated with cultivable resident strains are used to address this question. However, in Drosophila, this model has long eluded fly geneticists. In this issue of PLOS Biology, Pais and colleagues present the most rigorous and comprehensive demonstration to date that persistence and gut residency do take place in the digestive tract of Drosophila melanogaster. This natural gut isolate of Acetobacter thailandicus stably colonizes the adult fly foregut, accelerates larval maturation, and boosts host fecundity and fertility as efficiently as the known laboratory strains. The discovery of such stable association will be a boon for the Drosophila community interested in host-microbiota interaction, as it not only provides a novel model to unravel the molecular underpinnings of persistence but also opens a new arena for using Drosophila to study the implications of gut persistence in evolution and ecology.
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