Evidence map›Paper›PMID 30070715›Full record

ArticleHepatology (Baltimore, Md.)2019

Pulse Oximetry Is Insensitive for Detection of Hepatopulmonary Syndrome in Patients Evaluated for Liver Transplantation.

Kimberly A Forde, Michael B Fallon, Michael J Krowka, Michael Sprys, David S Goldberg, Karen L Krok, Mamta Patel, Grace Lin, Jae K Oh, Carl D Mottram and 3 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Hepatology (Baltimore, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Guideline
  2. Sorafenib in Hepatopulmonary Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2019
    Trial
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Unexplained Dyspnea: Hepatopulmonary Syndrome without Cirrhosis?Annals of the American Thoracic Society · 2023
    Article
  9. Hepatopulmonary syndrome.JHEP reports : innovation in hepatology · 2022
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Prevalence and Impact of Restrictive Lung Disease in Liver Transplant Candidates.Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society · 2020
    Article
  16. BMP9/10 in Pulmonary Vascular Complications of Liver Disease.American journal of respiratory and critical care medicine · 2020
    Article
  17. [Diagnosis and therapeutic strategies for hepatopulmonary syndrome].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2020
    Article
  18. Article
  19. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Kimberly A FordeDepartment of Medicine, University of Pennsylvania, Philadelphia, PA.
Michael B FallonDepartment of Medicine, University of Arizona, Phoenix, AZ.
Michael J KrowkaDepartment of Medicine, Mayo Clinic, Rochester, MN.
Michael SprysCenter for Clinical Epidemiology and Biostatistics, Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
David S GoldbergDepartment of Medicine, University of Pennsylvania, Philadelphia, PA.
Karen L KrokDepartment of Medicine, Penn State Milton S. Hershey Medical Center, Hershey, PA.
Mamta PatelDepartment of Medicine, University of Pennsylvania, Philadelphia, PA.
Grace LinDepartment of Medicine, Mayo Clinic, Rochester, MN.
Jae K OhDepartment of Medicine, Mayo Clinic, Rochester, MN.
Carl D MottramDepartment of Medicine, Mayo Clinic, Rochester, MN.
Paul D ScanlonDepartment of Medicine, Mayo Clinic, Rochester, MN.
Steven M KawutDepartment of Medicine, University of Pennsylvania, Philadelphia, PA.
Pulmonary Vascular Complications of Liver Disease 2 Study Group
Mayo Clinic in Arizona · USUniversity of Pennsylvania · USCenter for Clinical Research (United States) · USPenn State Milton S. Hershey Medical Center · USUniversity of Arizona · US

Funding

Sorafenib for Hepatopulmonary SyndromeUM1HL116886 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI FALLON, MICHAEL B, KAWUT, STEVEN M · 2013 to 2015
$5.1M
Estrogen signaling in portopulmonary hypertensionR01HL113988 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI FALLON, MICHAEL TODD, KAWUT, STEVEN M · 2012 to 2016
$3.8M
Mentored Patient-Oriented Research in Pulmonary Arterial HypertensionK24HL103844 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI KAWUT, STEVEN M · 2011 to 2020
$1.6M
Gender and hormonal influences on liver fibrosis after transplant for hepatitis CK23DK090209 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI FORDE, KIMBERLY AUTUMN · 2012 to 2016
$911k
A population-based cohort to study outcomes in end-stage liver disease patientsK08DK098272 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI GOLDBERG, DAVID SETH · 2013 to 2017
$786k
NHLBI NIH HHS K24 HL103844NHLBI NIH HHS R01 HL113988NHLBI NIH HHS UM1 HL116886NIDDK NIH HHS K08 DK098272NIDDK NIH HHS K23 DK090209
6 · The paper itself

Abstract

Screening for hepatopulmonary syndrome (HPS) using pulse oximetry is recommended in liver transplant (LT) candidates because mortality is increased, independently of the severity of the oxygenation defect. LT exception points may be afforded to those with HPS and severe hypoxemia. We assessed the screening characteristics of pulse oximetry for HPS. The Pulmonary Vascular Complications of Liver Disease 2 study is a multicenter, prospective cohort study of adults undergoing their first LT evaluation. Patients underwent protocolized assessment of oxygen saturation by pulse oximetry (SpO

Indexed as

Liver TransplantationOximetryFemaleHepatopulmonary SyndromeHumansMaleMiddle AgedPreoperative PeriodProspective StudiesSensitivity and Specificity

Identifiers

PMID30070715
PMCPMC6652183
OpenAlexW2887258100

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.