Evidence map›Paper›PMID 30069863›Full record

ArticleObesity surgery2018

Bariatric Surgery and Hepatocellular Carcinoma: a Propensity Score-Matched Analysis.

Basile Njei, Thomas R McCarty, Prabin Sharma, Andrew Lange, Nilofar Najafian, Julius N Ngu, Valmy E Ngomba, Justin B Echouffo-Tcheugui

Abstract read
In one paragraph

Article in Obesity surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. AGA Clinical Practice Update on Bariatric Surgery in Cirrhosis: Expert Review.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2021
    Guideline
  3. Review
  4. Review
  5. Observational
  6. Article
  7. Coffee, adenosine, and the liver.Purinergic signalling · 2024
    Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Bariatric and Metabolic Therapies Targeting the Small Intestine.Techniques and innovations in gastrointestinal endoscopy · 2020
    Article
  14. Review
  15. Article
  16. Article
  17. [Prevalence and harm of nonalcoholic fatty liver disease].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2019
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Basile NjeiSection of Digestive Diseases, Yale University School of Medicine, 333 Cedar St, New Haven, CT, 06520, USA. basile.njei@yale.edu.
Thomas R McCartyDepartment of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
Prabin SharmaDepartment of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
Andrew LangeDepartment of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
Nilofar NajafianDepartment of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
Julius N NguDepartment of Surgery, University of Texas Medical Branch, Galveston, TX, USA.
Valmy E NgombaDepartment of Internal Medicine, Richmond University Medical Center, Staten Island, NY, USA.
Justin B Echouffo-TcheuguiDivision of Endocrinology, Diabetes and Hypertension, Brigham and Women's Hospital, Boston, MA, USA.

Funding

Training Program in Investigative HepatologyT32DK007356 · NIDDK · YALE UNIVERSITY · PI MICHAEL H NATHANSON · 1986 to 2026
$7.4M
NIDDK NIH HHS T32 DK007356
6 · The paper itself

Abstract

backgroundThe association between obesity and rising incidence of hepatocellular carcinoma (HCC) in the USA has been documented; however, the role of bariatric surgery remains less clear.

aimTo evaluate the cross-sectional association of prior-bariatric surgery and HCC.

methodsThe United States Nationwide Inpatient Sample (NIS) database was queried from 2004 to 2014 for discharges with a diagnosis of morbid obesity. Primary outcomes of interest were HCC and in-hospital mortality rate. Secondary outcomes were length of stay and cost. Baseline characteristics were balanced using propensity score matching (PSM). Using Poisson and logistic regressions, adjusted HCC prevalence ratio (PR) and mortality odds ratio (OR) were derived in patients with prior-bariatric surgery compared to those without bariatric surgery.

resultsOf the 2,881,414 patients included in our study, 267,082 (9.3%) underwent bariatric surgery. From 2004 to 2014, there was a threefold increase in age-adjusted prevalence of HCC from 27 per 100,000 to 72 per 100,000 (P

conclusionIn this nationwide study of morbidly obese patients, prior-bariatric surgery was associated with a lower prevalence of HCC and lower in-patient mortality.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsObesity, MorbidBariatric SurgeryCross-Sectional StudiesHumansPropensity ScoreBariatric surgeryHepatocellular carcinoma (HCC)ObesityWeight loss

Identifiers

PMID30069863
PMCPMC6219901

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.