ArticleMolecular neurobiology2019
Resveratrol Modulates and Reverses the Age-Related Effect on Adenosine-Mediated Signalling in SAMP8 Mice.
Article in Molecular neurobiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 22 citations in OpenAlex.
- Adenosine APharmaceuticals (Basel, Switzerland) · 2026Article
- The Function of Microglia in Cognitive Impairment Influenced by Sleep Deprivation.Cellular and molecular neurobiology · 2026Review
- Mitochondrial Localization and Function of Adenosine Receptors.International journal of biological sciences · 2025Article
- The Potential Effects of Red Wine and Its Components on Neurocognitive Disorders: A Narrative Review.Nutrients · 2024Review
- Effect of Xanthohumol, a Bioactive Natural Compound from Hops, on Adenosine Pathway in Rat C6 Glioma and Human SH-SY5Y Neuroblastoma Cell Lines.Nutrients · 2024Article
- Compensatory cognition in neurological diseases and aging: A review of animal and human studies.Aging brain · 2023Review
- Neuroprotective Effects of Resveratrol by Modifying Cholesterol Metabolism and Aβ Processing in SAMP8 Mice.International journal of molecular sciences · 2022Article
- Resveratrol enhances AFrontiers in endocrinology · 2022Article
- Glutamate and GABA in Microglia-Neuron Cross-Talk in Alzheimer's Disease.International journal of molecular sciences · 2021Review
- High-Fat and Resveratrol Supplemented Diets Modulate Adenosine Receptors in the Cerebral Cortex of C57BL/6J and SAMP8 Mice.Nutrients · 2021Article
- C-Glucosylation as a tool for the prevention of PAINS-induced membrane dipole potential alterations.Scientific reports · 2021Article
- Antitumoral Action of Resveratrol Through Adenosinergic Signaling in C6 Glioma Cells.Frontiers in neuroscience · 2021Article
- Adenosine Metabolism in the Cerebral Cortex from Several Mice Models during Aging.International journal of molecular sciences · 2020Article
- Article
- Resveratrol: Multi-Targets Mechanism on Neurodegenerative Diseases Based on Network Pharmacology.Frontiers in pharmacology · 2020Article
- Modulation of Adenosine Receptors and Antioxidative Effect of Beer Extracts in in Vitro Models.Nutrients · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Resveratrol (RSV) is a natural compound present in berries, grapes and red wine that has shown some neuroprotective properties, but the mechanism by which RSV exhibits its protective role is not very well understood yet. Little is known about the effect of RSV on adenosinergic system, a system regulated in an age-dependent manner in SAMP8 mice, widely considered as an Alzheimer's model. Therefore, the aim of the present work was to assess whether RSV intake was able to modulate the adenosine-mediated signalling in SAMP8 mice. Data showed herein clearly demonstrate the ability of RSV to modulate adenosine receptor gene expression as well as transduction pathway mediated by receptors expressed on plasma membrane. Interestingly, this polyphenol was able to reverse the age-related loss of adenosine A
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Registered trials
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