Evidence map›Paper›PMID 30069805›Full record

ArticleEJNMMI physics2018

Inter-comparison of quantitative imaging of lutetium-177 (

Jill Wevrett, Andrew Fenwick, James Scuffham, Lena Johansson, Jonathan Gear, Susanne Schlögl, Marcel Segbers, Katarina Sjögreen-Gleisner, Pavel Solný, Michael Lassmann and 2 more

Abstract read
In one paragraph

Article in EJNMMI physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Milestones in dosimetry for nuclear medicine therapy.The British journal of radiology · 2022
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Recommendations for Multicentre Clinical Trials Involving Dosimetry for Molecular Radiotherapy.Clinical oncology (Royal College of Radiologists (Great Britain)) · 2021
    Article
  12. Article
  13. Journal of applied clinical medical physics · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jill WevrettUniversity of Surrey, Guildford, UK. Jill.Wevrett@nhs.net.
Andrew FenwickNational Physical Laboratory, Teddington, UK.
James ScuffhamUniversity of Surrey, Guildford, UK.
Lena JohanssonNational Physical Laboratory, Teddington, UK.
Jonathan GearThe Royal Marsden NHS Foundation Trust, Sutton, UK.
Susanne SchlöglUniversity Hospital of Wϋrzburg, Wϋrzburg, Germany.
Marcel SegbersErasmus University Medical Centre, Rotterdam, Netherlands.
Katarina Sjögreen-GleisnerDepartment of Medical Radiation Physics, Clinical Sciences Lund, Lund University, Lund, Sweden.
Pavel SolnýMotol University Hospital, Prague, Czech Republic.
Michael LassmannUniversity Hospital of Wϋrzburg, Wϋrzburg, Germany.
Jill TippingThe Christie NHS Foundation Trust, Manchester, UK.
Andrew NisbetUniversity of Surrey, Guildford, UK.

Funding

Engineering and Physical Sciences Research Council EP/L505675/1European Metrology Research Programme HLT11
6 · The paper itself

Abstract

backgroundThis inter-comparison exercise was performed to demonstrate the variability of quantitative SPECT/CT imaging for lutetium-177 (

resultsThe volumes reported by the participants for the inner section of the source were all within 29% of the true value and within 60% of the true value for the outer section. The activities reported by the participants for the inner section of the source were all within 20% of the true value, whilst those reported for the outer section were up to 83% different to the true value.

conclusionsA variety of calibration and segmentation methods were used by the participants for this exercise which demonstrated the variability of quantitative imaging across clinical sites. This paper presents a method to assess consistency between sites using different calibration and segmentation methods.

Indexed as

Lu-177LutetiumMolecular radiotherapyPRRTQuantitative imagingSPECT/CT

Identifiers

PMID30069805
PMCPMC6070453

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.