Evidence map›Paper›PMID 30069673›Full record

ArticleSleep & breathing = Schlaf & Atmung2018

Comparison of upper airway collapse patterns and its clinical significance: drug-induced sleep endoscopy in patients without obstructive sleep apnea, positional and non-positional obstructive sleep apnea.

C Kastoer, L B L Benoist, M Dieltjens, B Torensma, L H de Vries, P E Vonk, M J L Ravesloot, N de Vries

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 2 pooled it
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 2 syntheses or guidelines pooled it, 39 citations in OpenAlex.

  1. Drug-induced sleep endoscopy in obstructive sleep apnea: a systematic review and meta-analysis of sedative agents, monitoring methods, and administration techniques.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
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  9. Combination Tonsillectomy and Hypoglossal Nerve Stimulation for Sleep Apnea Patients With Oropharyngeal Lateral Wall Collapse.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

C KastoerDepartment of Otolaryngology Head and Neck Surgery, Antwerp University Hospital, Wilrijkstraat 10, 2650, Edegem, Antwerp, Belgium. Chloe.Kastoer@uza.be.ORCID http://orcid.org/0000-0002-4195-6944
L B L BenoistDepartment of Otorhinolaryngology Head and Neck Surgery, OLVG West, Amsterdam, The Netherlands.
M DieltjensDepartment of Otolaryngology Head and Neck Surgery, Antwerp University Hospital, Wilrijkstraat 10, 2650, Edegem, Antwerp, Belgium.
B TorensmaDepartment of Anaesthesiology, Leiden University Medical Center, Leiden, The Netherlands.
L H de VriesDepartment of Otorhinolaryngology Head and Neck Surgery, OLVG West, Amsterdam, The Netherlands.
P E VonkDepartment of Otorhinolaryngology Head and Neck Surgery, OLVG West, Amsterdam, The Netherlands.
M J L RaveslootDepartment of Otorhinolaryngology Head and Neck Surgery, OLVG West, Amsterdam, The Netherlands.
N de VriesDepartment of Otolaryngology Head and Neck Surgery, Antwerp University Hospital, Wilrijkstraat 10, 2650, Edegem, Antwerp, Belgium.
University of Antwerp · BEErasmus MC · NLLeiden University Medical Center · NLVincent Van Gogh Voor Geestelijke Gezondheidszorg · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare patient characteristics, upper airway (UA) collapse patterns and treatment outcome in obstructive sleep apnea (OSA) patients, including non-positional OSA patients (NPP) and positional OSA patients (PP), and non-OSA.

methodsCohort study of patients screened for OSA in 2012. Polysomnography was performed and UA was evaluated using the VOTE classification during drug-induced sleep endoscopy (DISE). Treatment outcome of MAD and UA surgery was evaluated.

resultsEight hundred sixty patients were included. Higher BMI, larger neck circumference, and greater age were independent significant predictors for OSA. DISE was performed in 543 patients: 119 non-OSA and 424 OSA patients of whom 257 PP and 167 NPP patients. PP were younger, had smaller neck circumference, lower BMI and apnea-hypopnea index (AHI) than NPP. Collapse at velum (p < 0.001) and oropharynx (p < 0.001) significantly increased the odds for having OSA. Tongue base and epiglottis collapse were, on group level, not determinative for OSA or non-OSA. Complete concentric collapse (CCC) was observed less frequently in PP (31.5%) as compared to NPP (46.1%). After UA surgery, OSA often was cured or improved to less severe positional OSA. Lower efficacy of UA surgery was observed in PP as compared to NPP. No differences were observed in MAD treatment outcome.

conclusionsCurrent study provides insight in patients screened for OSA: collapse at velum and oropharynx significantly determined presence of OSA and CCC occurred less frequently in PP compared to NPP. In addition, residual positional dependency is common after UA surgery. More trials are needed to gain insight in pathophysiology and treatment outcome.

Indexed as

Patient PositioningAdultAirway ObstructionBody Mass IndexBody WeightFemaleHumansMaleMiddle AgedNatural Orifice Endoscopic SurgeryPolysomnographySleep Apnea, ObstructiveSupine PositionObstructive sleep apneaPatternPhenotypingSedationSleep disordered breathingSupine dependency

Identifiers

PMID30069673
OpenAlexW2886532167

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.