Evidence map›Paper›PMID 30069619›Full record

Trial reportVeterinary research communications2018

A porcine-cholecyst-derived scaffold for treating full thickness lacerated skin wounds in dogs.

Satheesan Karthika, Sainulabdeen Anoop, C B Devanand, M K Narayanan, Madhavan Unni, Saji Eassow, Thapasimuthu Anilkumar

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Veterinary research communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Satheesan KarthikaDepartment of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, 680651, India. kittykat006@gmail.com.
Sainulabdeen AnoopDepartment of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, 680651, India.
C B DevanandDepartment of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, 680651, India.
M K NarayananDepartment of Veterinary Surgery and Radiology, College of Veterinary and Animal Sciences, Mannuthy, Thrissur, 680651, India.
Madhavan UnniDepartment Clinical Medicine, College of Veterinary and Animal Sciences, Mannuthy, 680651, India.
Saji EassowMeat Products of India Ltd. Edayar PO, Koothattukulam, 686662, India.
Thapasimuthu AnilkumarDivision of Experimental Pathology, Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, 695012, India.
Kerala Veterinary and Animal Sciences University · INSree Chitra Thirunal Institute for Medical Sciences and Technology · IN

Funding

Kerala Science Technology and Environment Committee No. 1275/2014/KSCSTESree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum TRC 8144
6 · The paper itself

Abstract

In regenerative medicine, despite the chances of graft-rejection, scaffolds prepared from extracellular matrices of various mammalian organs/tissues are widely used. Graft-assisted healing of full thickness skin-wounds is a major use of these bioscaffolds. Therefore, considering its prospective clinical use as a wound healing matrix, this study evaluated the healing potential of porcine cholecyst-derived scaffold (CDS) prepared by a non-detergent/enzymatic method for treating naturally occurring full thickness lacerated wounds in dogs. The CDS caused, in comparison with a commercial-grade bioscaffold prepared out of bovine dermal collagen (BDC), faster healing with respect to the wound healing parameters like peripheral tissue oedema, necrosis (amount and type), indurations, granulation tissue formation and the extent of re-epithelialisation. After 28 days of the treatment, the wound area (mean + SE) reduced from 27.60 ± 8.96 cm

Indexed as

Wound HealingAnimalsCollagenDogsExtracellular MatrixFemaleLacerationsMaleSkinSwineTissue ScaffoldsCollagenBioscaffoldGraft assisted healingRegenerative medicineWound planimetry

Identifiers

PMID30069619
OpenAlexW2885109751

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.