ArticleInternational orthopaedics2019
Microbiological profile and susceptibility pattern of surgical site infections related to orthopaedic trauma.
Article in International orthopaedics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07031999 (Use of Biocompatible Thermoplastic Impregnated With Vancomycin as a Temporary Orthopedic Spacer), which is not on this map. Cited by 22 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Use of Biocompatible Thermoplastic Impregnated With Vancomycin as a Temporary Orthopedic Spacer
Who cites it
22 citing papers in PubMed, 39 citations in OpenAlex.
- Surgical site infection after femoral fracture surgery: 5-year trends in mechanisms of injury, pathogens, and antimicrobial resistance.Journal of orthopaedic surgery and research · 2026Article
- Prevalence of Biofilm-Forming and Antibiotic-Resistant Coagulase-Negative Staphylococci Isolated from Hospitalized Patients in an Orthopedic Clinic.Pathogens (Basel, Switzerland) · 2026Article
- Additive Manufacturing, Thermoplastics, CAD Technology, and Reverse Engineering in Orthopedics and Neurosurgery-Applications to Preventions and Treatment of Infections.Antibiotics (Basel, Switzerland) · 2025Review
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- Orthopedic postoperative infection profile and antibiotic sensitivity of 2038 patients across 24 countries - Call for region and institution specific surgical antimicrobial prophylaxis.Journal of orthopaedics · 2024Article
- Prevalence and Antibiotic Resistance Patterns of Methicillin-ResistantIndian journal of microbiology · 2024Article
- A Bead Biofilm Reactor for High-Throughput Growth and Translational Applications.Microorganisms · 2024Article
- Facile fabrication of linezolid/strontium coated hydroxyapatite/graphene oxide nanocomposite for osteoporotic bone defect.Heliyon · 2024Article
- Carbon-infiltrated carbon nanotubes inhibit the development of Staphylococcus aureus biofilms.Scientific reports · 2023Article
- Trends in microbiological epidemiology of orthopedic infections: a large retrospective study from 2008 to 2021.BMC infectious diseases · 2023Article
- Potential application of menadione for antimicrobial coating of surgical sutures.Biotechnology notes (Amsterdam, Netherlands) · 2023Article
- The In Vivo and In Vitro Assessment of Pyocins in TreatingAntibiotics (Basel, Switzerland) · 2022Review
- Positive Bacterial Culture among Suspected Orthopedic Infections in a Tertiary Care Centre: A Descriptive Cross-sectional Study.JNMA; journal of the Nepal Medical Association · 2022Article
- Evaluation of Staphylococcus aureus and Candida albicans biofilms adherence to PEEK and titanium-alloy prosthetic spine devices.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2022Article
- Microbiological Profile and Drug Resistance Analysis of Postoperative Infections following Orthopedic Surgery: A 5-Year Retrospective Review.Advances in orthopedics · 2022Article
- Recent Advances in the Evaluation of Antimicrobial Materials for Resolution of Orthopedic Implant-Associated InfectionsACS infectious diseases · 2021Review
- Direct detection of microorganisms in sonicated orthopedic devices after in vitro biofilm production and different processing conditions.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2021Article
- Application of MALDI-TOF MS Profiling Coupled With Functionalized Magnetic Enrichment for Rapid Identification of Pathogens in a Patient With Open Fracture.Frontiers in chemistry · 2021Article
- Bacterial Profile, Multi-Drug Resistance and Seasonality Following Lower Limb Orthopaedic Surgery in Tropical and Subtropical Australian Hospitals: An Epidemiological Cohort Study.International journal of environmental research and public health · 2020Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundUnderstanding the epidemiology of microorganisms associated with surgical site infections related to orthopaedic trauma (SSI-ROT) is important in establishing treatment protocols. The aim of this study was to evaluate the etiology and susceptibility pattern of SSIs related to orthopaedic trauma in a Brazilian reference hospital for trauma.
methodsPatients with SSI-ROT in a Brazilian reference hospital for trauma were retrospectively analyzed. All patients with orthopaedic trauma who underwent a surgical procedure and developed SSI within one year were included. All patients had culture samples from the surgical site obtained from biopsy of bone or soft tissue. Clinical and epidemiological data of the patients were collected.
resultsA total of 147 patients with trauma-related infection were included in the analysis. The mean time to infection was 55.5 days, and the mean duration of hospitalization was 20.0 days. The in-hospital mortality rate after infection was 5.4%. Cultures were obtained from all patients, with 104 samples obtained from soft tissues and 43 samples from bone. The positivity rate was 93.2%. Among the isolates, 56.5% (77 patients) were gram-negative bacteria and 43.8% (60 patients) were gram-positive bacteria. Staphylococcus aureus was identified in 34%, Enterobacter spp. in 14.9%, and Pseudomonas aeruginosa in 11.6%. Staphylococcus aureus presented a higher positivity in bone samples (odds ratio, 1.29; 95% CI, 1.01-1.70; p = 0.04). Few microorganisms were multi-resistant.
conclusionSSI in orthopaedic trauma can be associated with gram-negative bacilli, the susceptibility profile of which suggested that most infections occur after discharge. Staphylococcus aureus infections were commonly caused by methicillin-susceptible isolates, and this susceptibility to oral antibiotic options helps in the dehospitalization of patients.
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