Trial reportInternational orthopaedics2019
Fixation of periprosthetic or osteoporotic distal femoral fractures with locking plates: a pilot randomised controlled trial.
Trial report in International orthopaedics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 3 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Weightbearing versus non-weight bearing in geriatric distal femoral fractures: a systematic review and meta-analysis.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024Pooled it
- Interventions for treating fractures of the distal femur in adults.The Cochrane database of systematic reviews · 2022Pooled it
- Cost-effectiveness of fixation versus arthroplasty for geriatric distal femur fractures.Injury · 2022Pooled it
- Fixation strategies for periprosthetic femur fractures around knee replacements: a comprehensive single-center analysis of 102 consecutive cases.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Callus formation during healing is guided by local strain: a retrospective clinical observation.BMC musculoskeletal disorders · 2026Observational
- Optimizing plate working length and screw configuration for femoral shaft plate fixation: a finite element analysis under different bone quality scenarios.BMC musculoskeletal disorders · 2026Article
- Mechanical Performance of Monoaxial Versus Polyaxial Locked Plates for Bone Fracture Repair: A Review.Clinics in orthopedic surgery · 2026Review
- Quality of Life Following Vancouver Type B Periprosthetic Femoral Fractures: A Cross-Sectional Study.Medicina (Kaunas, Lithuania) · 2025Article
- [Polyaxial angle stability].Unfallchirurgie (Heidelberg, Germany) · 2025Review
- Prospective study on functional outcome of distal femur fracture treated by open reduction and internal fixation using distal femur locking plate in Tibebe Ghion Specialized Hospital, Bahirdar, North West Ethiopia.Journal of orthopaedic surgery and research · 2024Article
- Consensus review on peri-implant femur fracture treatment: Peri-Implant Spanish Consensus (PISCO) investigators' recommendations.EFORT open reviews · 2024Review
- Periprosthetic fracture management of the proximal femur.OTA international : the open access journal of orthopaedic trauma · 2023Review
- Revision rate is higher in patients with periprosthetic femur fractures following revision arthroplasty in comparison with ORIF following our algorithm: a two-center 1 analysis of 129 patients.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Article
- [Current status and progress of locking plate in the treatment of distal femoral comminuted fracture].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2021Article
- Immediate Full Weight-Bearing Versus Partial Weight-Bearing After Plate Fixation of Distal Femur Fractures in Elderly Patients. A Randomized Controlled Trial.Geriatric orthopaedic surgery & rehabilitation · 2021Article
- Periprosthetic hip fractures: an update into their management and clinical outcomes.EFORT open reviews · 2021Review
- Functional outcome of open distal femoral fractures managed with lateral locking plates.International orthopaedics · 2020Observational
- High mortality following distal femur fractures: a cohort study including three hundred and two distal femur fractures.International orthopaedics · 2020Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionWe hypothesised that the use of a polyaxial locking plate design offers the same clinical benefits as a monoaxial locking plate system following distal femoral osteoporotic/periprosthetic fracture fixation.
methodA multicentre prospective randomised pilot trial was conducted. Inclusion criteria were patients over 60 years with a displaced osteoporotic or periprosthetic distal femoral fracture. Details documented included time to union, complications, reinterventions and functional outcomes according to the Oxford knee score and EuroQol EQ-5D. Analysis of factors influencing an early fracture healing response was performed between those with clear features of radiological callus formation at three months. Statistical analysis was performed using a logistic regression model with multiple covariates assessed for each plate system (1:1 ratio) over a follow-up period of one year.
resultsForty patients (34 females) with a mean age of 77 (60-99) were recruited. Four patients deceased within the first six months. Twenty-five patients united by the six month follow-up. Six more patients progressed to union between six and nine months. Five patients developed non-union (two patients had implant failure; one in each group) and all underwent revision surgery. Malunion was evident in two cases, one with 15° of valgus (monoaxial plate), and one with 12° of recurvatum (polyaxial plate). Between the two plate systems, statistical analysis revealed no significant differences in most of the recorded parameters. Radiological features of early bone healing were present when the surgical approach was smaller (p = 0.015), and when a greater working length of the bridging plate was present (p = 0.016).
conclusionBoth plate systems demonstrated good union rates and limited implant related complications. Good reduction, mechanically sound construct and respect of the local fracture biology was more important than the particular plate design characteristics.
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