Evidence map›Paper›PMID 30069288›Full record

ArticleNeurology international2018

Cognitive impairment in neuromuscular diseases: A systematic review.

Marco Orsini, Ana Carolina, Andorinho de F Ferreira, Anna Carolina Damm de Assis, Thais Magalhães, Silmar Teixeira, Victor Hugo Bastos, Victor Marinho, Thomaz Oliveira, Rossano Fiorelli and 2 more

Open access · goldAbstract read
In one paragraph

Article in Neurology international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Marco OrsiniMaster's Program in Health Applied Sciences, Severino Sombra University, Vasssouras, Rio de Janeiro.
Ana CarolinaMaster's Program in Health Applied Sciences, Severino Sombra University, Vasssouras, Rio de Janeiro.
Andorinho de F FerreiraDepartment of Neurology, Federal Fluminense University, Rio de Janeiro.
Anna Carolina Damm de AssisDepartment of Neurology, Federal Fluminense University, Rio de Janeiro.
Thais MagalhãesDepartment of Neurology, Federal Fluminense University, Rio de Janeiro.
Silmar TeixeiraBrain Mapping and Plasticity Laboratory, Federal University of Piauí, Parnaíba.
Victor Hugo BastosBrain Mapping and Plasticity Laboratory, Federal University of Piauí, Parnaíba.
Victor MarinhoBrain Mapping and Plasticity Laboratory, Federal University of Piauí, Parnaíba.
Thomaz OliveiraBrain Mapping and Plasticity Laboratory, Federal University of Piauí, Parnaíba.
Rossano FiorelliMaster's Program in Health Applied Sciences, Severino Sombra University, Vasssouras, Rio de Janeiro.
Acary Bulle OliveiraDepartment of Neurology, Federal University of São Paulo.
Marcos R G de FreitasDepartment of Neurology, Federal University of Rio de Janeiro, Brazil.
Universidade Federal do Piauí · BRUniversidade Federal de São Paulo · BRUniversidade Federal Fluminense · BRUniversidade Federal do Rio de Janeiro · BRUniversity of Vassouras · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuromuscular diseases are multifactorial pathologies characterized by extensive muscle fiber damage that leads to the activation of satellite cells and to the exhaustion of their pool, with consequent impairment of neurobiological aspects, such as cognition and motor control. To review the knowledge and obtain a broad view of the cognitive impairment on Neuromuscular Diseases. Cognitive impairment in neuromuscular disease was explored; a literature search up to October 2017 was conducted, including experimental studies, case reports and reviews written in English. Keywords included Cognitive Impairment, Neuromuscular Diseases, Motor Neuron Diseases, Dystrophinopathies and Mitochondrial Disorders. Several cognitive evaluation scales, neuroimaging scans, genetic analysis and laboratory applications in neuromuscular diseases, especially when it comes to the Motor Neuron Diseases, Dystrophinopathies and Mitochondrial Disorders. In addition, organisms model using rats in the genetic analysis and laboratory applications to verify the cognitive and neuromuscular impacts. Several studies indicate that congenital molecular alterations in neuromuscular diseases promote cognitive dysfunctions. Understanding these mechanisms may in the future guide the proper management of the patient, evaluation, establishment of prognosis, choice of treatment and development of innovative interventions such as gene therapy.

Indexed as

Cognitive ImpairmentDystrophinopathiesMitochondrial DisordersMotor Neuron DiseasesNeuromuscular Diseases

Identifiers

PMID30069288
PMCPMC6050451
OpenAlexW2883261096

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.