Evidence map›Paper›PMID 30069239›Full record

ArticleMaedica2018

Pain in Patients with Multiple Sclerosis.

Mahsa Ghajarzadeh, Rozita Jalilian, Mohammad Ali Sahraian, Abdorreza Naser Moghadasi, Amirreza Azimi, Mehdi Mohammadifar, Sepehr Azizi

Abstract read
In one paragraph

Article in Maedica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Maternal diabetes as a prenatal risk factor for multiple sclerosis in offspring: a systematic review and meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Pooled it
  2. Invisible symptoms and associated factors in multiple sclerosis patients.Journal of education and health promotion · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Bladder Dysfunction in Iranian Patients with Multiple Sclerosis.Journal of multidisciplinary healthcare · 2020
    Article
  10. Article
  11. Article
  12. Cannabinoids for spasticity in patients with multiple sclerosis: A systematic review and meta-analysis.Multiple sclerosis journal - experimental, translational and clinical
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mahsa GhajarzadehUniversal Council of Epidemiology (UCE), Universal Scientific Education and Research Network (USERN), Tehran, Iran.
Rozita JalilianTehran University of Medical Sciences, Tehran, Iran.
Mohammad Ali SahraianTehran University of Medical Sciences, Tehran, Iran.
Abdorreza Naser MoghadasiTehran University of Medical Sciences, Tehran, Iran.
Amirreza AzimiTehran University of Medical Sciences, Tehran, Iran.
Mehdi MohammadifarDepartment of Radiology, Zanjan University of Medical Sciences, Zanjan, Iran.
Sepehr AziziIran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMultiple sclerosis is a chronic inflammatory disease which affects the central nervous system. Many patients with multiple sclerosis suffer from persistent pain during the disease course. In Iranian cases, pain has not been regarded as it should be.

objectiveThe goal of this study was to determine the prevalence and types of pain in Iranian multiple sclerosis patients. MATERIAL AND

methodsThis cross sectional study was conducted in the multiple sclerosis clinic of Sina Hospital between October 2014 and August 2015. Eighty eight multiple sclerosis patients were enrolled. Participants were asked to fill a valid and reliable Persian version of the Brief Pain Inventory. Demographic data (sex, age), disease duration and disease course were extracted from patients' medical files. All patients were examined by an expert neurologist to obtain Kurtzke Expanded Disability Status Scale (EDSS).

resultsThe mean age and mean duration of disease were 30.4±7.6 years and 5.9±4 years, respectively. Median EDSS was 1. All patients reported pain. The most common sites of pain were upper extremities (52.3%). Higher the EDSS score, higher pain interference with the evaluated items. By using the worst pain intensity as a dependent variable, and age, sex, EDSS, disease duration and type of disease as independent variables, regression analysis showed that the EDSS score was an independent predictor for the intensity of pain in this group of patients.

conclusionPain is a common symptom found in patients diagnosed with multiple sclerosis. Thus, an accurate and thorough assessment of pain should be integrated in the routine evaluation of patients diagnosed with multiple sclerosis.

Identifiers

PMID30069239
PMCPMC6060297

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.