Evidence map›Paper›PMID 30069207›Full record

ArticleIranian journal of parasitology

Construction of an Adenovirus Vaccine Expressing the Cross-reactive Antigen AMA1 for

Lijun Jia, Huanping Guo, Mingming Liu, Yang Gao, Lei Zhang, Hang Li, Suzhu Xie, Ningning Zhang

Abstract read
PubMed Full text at PMC
In one paragraph

Article in Iranian journal of parasitology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Vaccines · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lijun JiaDept. of Veterinary Medicine, Agricultural College of Yanbian University, Yanji, Jilin 133000, China.
Huanping GuoNational Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan.
Mingming LiuNational Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan.
Yang GaoNational Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido 080-8555, Japan.
Lei ZhangDept. of Veterinary Medicine, Agricultural College of Yanbian University, Yanji, Jilin 133000, China.
Hang LiDept. of Veterinary Medicine, Agricultural College of Yanbian University, Yanji, Jilin 133000, China.
Suzhu XieDept. of Veterinary Medicine, Agricultural College of Yanbian University, Yanji, Jilin 133000, China.
Ningning ZhangDept. of Veterinary Medicine, Agricultural College of Yanbian University, Yanji, Jilin 133000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe aimed to construct an adenovirus expressing a cross-reactive fragment of the apical membrane antigen 1 (AMA1) antigen and evaluated the concomitant immune response in BABL/c mice, allowing protection against

methodsThe study was conducted in Agricultural College of Yanbian University, Yanji, Jilin, China In 2015-2016. Primers were designed using the AMA1 gene sequences of

resultsThe level of IgG in BABL/c mice immunized with Ad5-NcAMA1 was significantly increased when compared with that of pVAX1-NcAMA1 and PBS groups (

conclusionThe adenovirus vaccineAd5-NcAMA1 could provide protective immunity against

Indexed as

AMA1 geneImmune responseNeospora caninumRecombinant adenovirusToxoplasma gondii

Identifiers

PMID30069207
PMCPMC6068368

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.