Evidence map›Paper›PMID 30069047›Full record

ArticleNature2018

Karyotype engineering by chromosome fusion leads to reproductive isolation in yeast.

Jingchuan Luo, Xiaoji Sun, Brendan P Cormack, Jef D Boeke

Open access · greenAbstract read
In one paragraph

Article in Nature, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 176 citations in OpenAlex.

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  12. Chromosomal structural variation loci HSS1 and HSS6 lead to hybrid sterility in rice.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025
    Article
  13. Convergent Patterns of Karyotype Evolution Underlying Karyotype Uniformity in Conifers.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
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35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jingchuan LuoInstitute for Systems Genetics, NYU Langone Health, New York, NY, USA.
Xiaoji SunInstitute for Systems Genetics, NYU Langone Health, New York, NY, USA.
Brendan P CormackDepartment of Molecular Biology & Genetics, JHU School of Medicine, Baltimore, MD, USA.
Jef D BoekeInstitute for Systems Genetics, NYU Langone Health, New York, NY, USA. jef.boeke@nyumc.org.
Institute for Systems Biology · USJohns Hopkins University · US

Funding

AIDS Opportunistic Infectious: Virulence of C. glabrataR01AI046223 · NIAID · JOHNS HOPKINS UNIVERSITY · PI CORMACK, BRENDAN · 1999 to 2014
$4.9M
National Science Foundation MCB-1616111NIAID NIH HHS R01 AI046223
6 · The paper itself

Abstract

Extant species have wildly different numbers of chromosomes, even among taxa with relatively similar genome sizes (for example, insects)

Indexed as

Gene EditingKaryotypeArtificial Gene FusionChromosomes, FungalCRISPR-Cas SystemsCrosses, GeneticMicrobial ViabilityReproductionSaccharomyces cerevisiaeSpores, Fungal

Identifiers

PMID30069047
PMCPMC8223741
OpenAlexW2886843464

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.