ArticleNature communications2018
Optimal control theory enables homonuclear decoupling without Bloch-Siegert shifts in NMR spectroscopy.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Optimal control of spin systems.Science advances · 2026Review
- Human cells for human proteins: Isotope labeling in mammalian cells in suspension for functional NMR studies.Protein science : a publication of the Protein Society · 2026Article
- Responses to Ligand Binding in the Bacterial DNA Sliding Clamp "β-Clamp" Manifest in Dynamic Allosteric Effects.Proteins · 2025Article
- Seedless: on-the-fly pulse calculation for NMR experiments.Nature communications · 2025Article
- Leveraging relaxation-optimizedNature chemistry · 2025Article
- OptimizedInternational journal of molecular sciences · 2025Article
- Homonuclear Super-Resolution NMR Spectroscopy.Angewandte Chemie (International ed. in English) · 2024Article
- Protein NMR assignment by isotope pattern recognition.Science advances · 2024Article
- Optimal control pulses for the 1.2-GHz (28.2-T) NMR spectrometers.Science advances · 2023Article
- Improved Detection and Quantification of Cyclopropane Fatty Acids via Homonuclear Decoupling Double Irradiation NMR Methods.ACS omega · 2023Article
- Direct Modulators of K-Ras-Membrane Interactions.ACS chemical biology · 2023Article
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- Chemical and structural approaches to investigate PTEN function and regulation.Methods in enzymology · 2023Article
- Band-selective universal 90° and 180° rotation pulses covering the aliphatic carbon chemical shift range for triple resonance experiments on 1.2 GHz spectrometers.Journal of biomolecular NMR · 2022Article
- Article
- The structural basis of PTEN regulation by multi-site phosphorylation.Nature structural & molecular biology · 2021Article
- Optimization of phase dispersion enables broadband excitation without homonuclear coupling artifacts.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2021Article
- Nearest-neighbor NMR spectroscopy: categorizing spectral peaks by their adjacent nuclei.Nature communications · 2020Article
- The structural determinants of PH domain-mediated regulation of Akt revealed by segmental labeling.eLife · 2020Article
- Emerging solution NMR methods to illuminate the structural and dynamic properties of proteins.Current opinion in structural biology · 2019Review
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7 authors.
Funding
Abstract
The Bloch-Siegert shift is a phenomenon in NMR spectroscopy and atomic physics in which the observed resonance frequency is changed by the presence of an off-resonance applied field. In NMR, it occurs especially in the context of homonuclear decoupling. Here we develop a practical method for homonuclear decoupling that avoids inducing Bloch-Siegert shifts. This approach enables accurate observation of the resonance frequencies of decoupled nuclear spins. We apply this method to increase the resolution of the HNCA experiment. We also observe a doubling in sensitivity for a 30 kDa protein. We demonstrate the use of band-selective C
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