Evidence map›Paper›PMID 30068738›Full record

ReviewClinical microbiology reviews2018

Mobile Genetic Elements Associated with Antimicrobial Resistance.

Sally R Partridge, Stephen M Kwong, Neville Firth, Slade O Jensen

Open access · bronzeAbstract readReview
In one paragraph

Review in Clinical microbiology reviews, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1,370 papers.

0numbers the graph read from it
0cells of the map it votes in
1,370citing papers in PubMed
51.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1,370 citing papers in PubMed, 2,437 citations in OpenAlex.

  1. Article
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  6. Review
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  10. Molecular Characterization of vanA and blaMolecular biology reports · 2026
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  11. Article
  12. Characterization of defensome genes and mobile genetic Elements in different types of pasture soil agroecosystems from the Brazilian Amazon.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  13. Article
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  15. Specific host translation perturbations promote TnbioRxiv : the preprint server for biology · 2026
    Article
  16. Article
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  20. Review

1,310 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Sally R PartridgeCentre for Infectious Diseases and Microbiology, The Westmead Institute for Medical Research, The University of Sydney and Westmead Hospital, Westmead, New South Wales, Australia sally.partridge@health.nsw.gov.au S.Jensen@westernsydney.edu.au.
Stephen M KwongSchool of Life and Environmental Sciences, University of Sydney, Sydney, New South Wales, Australia.
Neville FirthSchool of Life and Environmental Sciences, University of Sydney, Sydney, New South Wales, Australia.
Slade O JensenMicrobiology and Infectious Diseases, School of Medicine, Western Sydney University, Sydney, New South Wales, Australia sally.partridge@health.nsw.gov.au S.Jensen@westernsydney.edu.au.
The University of Sydney · AUIngham Institute · AUWestmead Institute for Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Strains of bacteria resistant to antibiotics, particularly those that are multiresistant, are an increasing major health care problem around the world. It is now abundantly clear that both Gram-negative and Gram-positive bacteria are able to meet the evolutionary challenge of combating antimicrobial chemotherapy, often by acquiring preexisting resistance determinants from the bacterial gene pool. This is achieved through the concerted activities of mobile genetic elements able to move within or between DNA molecules, which include insertion sequences, transposons, and gene cassettes/integrons, and those that are able to transfer between bacterial cells, such as plasmids and integrative conjugative elements. Together these elements play a central role in facilitating horizontal genetic exchange and therefore promote the acquisition and spread of resistance genes. This review aims to outline the characteristics of the major types of mobile genetic elements involved in acquisition and spread of antibiotic resistance in both Gram-negative and Gram-positive bacteria, focusing on the so-called ESKAPEE group of organisms (

Indexed as

DNA Transposable ElementsGene Transfer, HorizontalAnti-Bacterial AgentsBacteriaBacterial InfectionsBiological EvolutionDrug Resistance, BacterialAnti-Bacterial AgentsDNA Transposable Elementsantibiotic resistancegene cassetteinsertion sequenceintegrative conjugative elementintegronplasmidresistance islandtransposon

Identifiers

PMID30068738
PMCPMC6148190
OpenAlexW2885680427

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.