ArticleCold Spring Harbor molecular case studies2018
Germline
Open access · diamondAbstract read
In one paragraph
Article in Cold Spring Harbor molecular case studies, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 45 citations in OpenAlex.
- Diagnostic yield of cancer predisposition in a nationwide prospective childhood acute leukemia cohort.Nature communications · 2026Article
- Prenatally Detected Neonatal Neuroblastoma Associated with Achondroplasia and an SDHA Variant.Neurology international · 2026Article
- Article
- Germline genomic profiling of patients with early-onset colorectal cancer.ESMO gastrointestinal oncology · 2025Article
- Proteogenomic characterisation of primary oral cancer unveils extracellular matrix remodelling and immunosuppressive microenvironment linked to lymph node metastasis.Clinical and translational medicine · 2025Article
- Massive paraganglioma masquerading as ovarian tumor: a unique case of paraganglioma of undetermined genetic origin.Proceedings (Baylor University. Medical Center) · 2025Article
- SDHA-related phaeochromocytoma and paraganglioma: review and clinical management.Endocrine-related cancer · 2024Review
- Knowledge-Based Therapeutics for Tricarboxylic Acid (TCA) Cycle-Deficient Cancers.Cold Spring Harbor perspectives in medicine · 2024Review
- Combined Germline and Mosaic SDHA Mutation Is Associated With a Multicancer Syndrome Including Neuroblastoma, Renal Cancer, and Multifocal GI Tumor.JCO precision oncology · 2024Article
- Article
- Hereditary Renal Cell Carcinoma Syndromes.Hematology/oncology clinics of North America · 2023Review
- The Impact of Germline Alterations in Appendiceal Adenocarcinoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023Article
- Review
- UK recommendations forJournal of medical genetics · 2023Article
- Identification of Germline Variants in Patients with Hereditary Cancer Syndromes in Northeast Mexico.Genes · 2023Article
- Expanded genetic testing of GIST patients identifies high proportion of non-syndromic patients with germline alterations.NPJ precision oncology · 2023Article
- Co-occurrence ofFrontiers in oncology · 2022Article
- Mitochondrial dysfunction, UPRCell & bioscience · 2021Review
- Role of Energy Metabolism in the Progression of Neuroblastoma.International journal of molecular sciences · 2021Review
- Familial wild-type gastrointestinal stromal tumour in association with germline truncating variants in both SDHA and PALB2.European journal of human genetics : EJHG · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
38 authors at 4 institutions in 1 country.
Marianne Dubard GaultGraduate Education Memorial, Memorial Sloan Kettering Cancer Center and Weill Cornell Genetics, New York, New York 10065, USA.
Diana MandelkerDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Deborah DeLairDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Carolyn R StewartDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Yelena KemelDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Margaret R SheehanDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Beth SiegelDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Jennifer KennedyDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Vanessa MarcellDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Angela ArnoldDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Hikmat Al-AhmadieDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Shakeel ModakDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Mark RobsonDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Neerav ShuklaDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Stephen RobertsDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Joseph VijaiDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Sabine TopkaNiehaus Center for Inherited Cancer Genomics, Clinical Genetics Service, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Alex KentsisDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Karen CadooDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Maria CarloDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Alicia Latham SchwarkGraduate Education Memorial, Memorial Sloan Kettering Cancer Center and Weill Cornell Genetics, New York, New York 10065, USA.
Ed ReznikSloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Renzo DinataleSloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Jaclyn HechtmanDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Ester Borras FloresDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Sowmaya JairamDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Ciyu YangDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Yirong LiDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Erol Can BayraktarRockefeller University, New York, New York 10021, USA.
Ozge Ceyhan-BirsoyDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Liying ZhangDepartment of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Wendy KohlmanFamily Cancer Assessment Clinic, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA.
Joshua SchiffmanFamily Cancer Assessment Clinic, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA.
Zsofia StadlerDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Kivanc BirsoyFamily Cancer Assessment Clinic, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA.
Andrew KungDepartment of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Kenneth OffitDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Michael F WalshDepartment of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA.
Memorial Sloan Kettering Cancer Center · USHuntsman Cancer Institute · USRockefeller University · USUniversity of Utah · US
Funding
X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4MStructure and function of genome plasticity in human cancerR01CA214812 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI KENTSIS, ALEX · 2018 to 2022
$2.5MNCI NIH HHS P30 CA008748NCI NIH HHS R01 CA214812
Abstract
Mutations in succinate dehydrogenase complex genes predispose to familial paraganglioma-pheochromocytoma syndrome (FPG) and gastrointestinal stromal tumors (GIST). Here we describe cancer patients undergoing agnostic germline testing at Memorial Sloan Kettering Cancer Center and found to harbor germline
Indexed as
Germ-Line MutationAdolescentAdultCell Line, TumorChildChild, PreschoolElectron Transport Complex IIFemaleGene FrequencyHEK293 CellsHumansMaleMiddle AgedNeoplasmsElectron Transport Complex IISDHA protein, humanclear cell renal cell carcinomagastrointestinal stroma tumorneoplasm of the breastneuroblastoma
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY-NC
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.