Evidence map›Paper›PMID 30068702›Full record

ArticleGenes & development2018

Overgrowth syndromes and pediatric cancers: how many roads lead to

Ruthrothaselvi Bharathavikru, Nicholas D Hastie

Open access · diamondAbstract readComment
In one paragraph

Article in Genes & development, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ruthrothaselvi BharathavikruMedical Research Council, Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, United Kingdom.
Nicholas D HastieMedical Research Council, Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, United Kingdom.
Western General Hospital · GB

Funding

Medical Research Council MR/N020405/1
6 · The paper itself

Abstract

Overgrowth syndromes such as Perlman syndrome and associated pediatric cancers, including Wilms tumor, arise through genetic and, in certain instances, also epigenetic changes. In the case of the Beckwith-Wiedemann overgrowth syndrome and in Wilms tumor, increased levels of

Indexed as

Wilms TumorAnimalsChildExoribonucleasesFemaleFetal MacrosomiaHumansInsulin-Like Growth Factor IIMiceNephronsPregnancyStem CellsSyndromeUp-RegulationDIS3L2 protein, humanDis3l2 protein, mouseExoribonucleasesIGF2 protein, humanInsulin-Like Growth Factor IIDIS3L2IGF2LIN28microRNApediatric cancerPerlman syndromeWilms tumor

Identifiers

PMID30068702
PMCPMC6075144
OpenAlexW2885027264

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.