Evidence map›Paper›PMID 30068680›Full record

ArticleProceedings. Biological sciences2018

Adaptive evolution of distinct prey-specific toxin genes in rear-fanged snake venom.

Cassandra M Modahl, Mrinalini, Seth Frietze, Stephen P Mackessy

Erratum issuedAbstract read
In one paragraph

Article in Proceedings. Biological sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed.

  1. Article
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  5. Comparative Hemostatic Effects ofBiochemistry research international · 2026
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  7. Article
  8. Review
  9. Article
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  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Venom phenotype conservation suggests integrated specialization in a lizard-eating snake.Toxicon : official journal of the International Society on Toxinology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Cassandra M ModahlSchool of Biological Sciences, University of Northern Colorado, 501 20th Street, Greeley, CO 80639-0017, USA.
MrinaliniDepartment of Biological Sciences, National University of Singapore, Singapore 117543, Republic of Singapore.
Seth FrietzeSchool of Biological Sciences, University of Northern Colorado, 501 20th Street, Greeley, CO 80639-0017, USA.
Stephen P MackessySchool of Biological Sciences, University of Northern Colorado, 501 20th Street, Greeley, CO 80639-0017, USA stephen.mackessy@unco.edu.ORCID 0000-0003-4515-2545

Funding

VERMONT IMMUNOBIOLOIGY/ INFECTIOUS DISEASES CENTERP20RR021905 · NCRR · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI BUDD, RALPH C · 2006 to 2011
$14.5M
Vermont Immunology/Infectious Diseases CenterP30GM118228 · NIGMS · UNIVERSITY OF VERMONT & ST AGRIC COLLEGE · PI BUDD, RALPH C · 2016 to 2021
$6.8M
NCRR NIH HHS P20 RR021905NIGMS NIH HHS P30 GM118228
6 · The paper itself

Abstract

Venom proteins evolve rapidly, and as a trophic adaptation are excellent models for predator-prey evolutionary studies. The key to a deeper understanding of venom evolution is an integrated approach, combining prey assays with analysis of venom gene expression and venom phenotype. Here, we use such an approach to study venom evolution in the Amazon puffing snake,

Indexed as

Amino Acid SequenceAnimalsBiological EvolutionColubridaeGene ExpressionLizardsMiceProtein ConformationSnake VenomsSnake Venomsadaptationgene duplicationproteomestructure-functiontaxon-specific toxintranscriptome

Identifiers

PMID30068680
PMCPMC6111164

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.