Evidence map›Paper›PMID 30068648›Full record

ArticleJournal of virology2018

Surfactin Inhibits Membrane Fusion during Invasion of Epithelial Cells by Enveloped Viruses.

Lvfeng Yuan, Shuai Zhang, Yongheng Wang, Yuchen Li, Xiaoqing Wang, Qian Yang

Open access · bronzeAbstract read
In one paragraph

Article in Journal of virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 1 pooled it
7.1field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 1 synthesis or guideline pooled it, 121 citations in OpenAlex.

  1. The Surfactin-Like Lipopeptides FromFrontiers in bioengineering and biotechnology · 2021
    Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Dissecting the role ofFrontiers in microbiology · 2026
    Article
  8. Article
  9. Article
  10. Membrane-Targeting Antivirals.International journal of molecular sciences · 2025
    Review
  11. Review
  12. Veterinary sciences · 2025
    Article
  13. In Vitro and In Vivo Evaluation ofAnimals : an open access journal from MDPI · 2025
    Article
  14. Antimicrobial Activity ofInternational journal of molecular sciences · 2025
    Review
  15. Article
  16. Winning the battle of intestinal peace withFrontiers in microbiology · 2025
    Review
  17. Review
  18. Frontiers in cellular and infection microbiology · 2025
    Article
  19. Review
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lvfeng YuanMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University. Nanjing, Jiangsu, People's Republic of China.
Shuai ZhangMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University. Nanjing, Jiangsu, People's Republic of China.
Yongheng WangMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University. Nanjing, Jiangsu, People's Republic of China.
Yuchen LiMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University. Nanjing, Jiangsu, People's Republic of China.
Xiaoqing WangMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University. Nanjing, Jiangsu, People's Republic of China.
Qian YangMOE Joint International Research Laboratory of Animal Health and Food Safety, College of Veterinary Medicine, Nanjing Agricultural University. Nanjing, Jiangsu, People's Republic of China zxbyq@njau.edu.cn.
Nanjing Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Because membrane fusion is a crucial step in the process by which enveloped viruses invade host cells, membrane fusion inhibitors can be effective drugs against enveloped viruses. We found that surfactin from

Indexed as

AnimalsAntiviral AgentsBacillus subtilisCell LineCell MembraneEpithelial CellsLipopeptidesMiceMice, Inbred BALB CPeptides, CyclicPorcine epidemic diarrhea virusSwineTransmissible gastroenteritis virusVirus AttachmentVirus InternalizationAntiviral AgentsLipopeptidesPeptides, Cyclicsurfactin peptideenveloped virusfusion inhibitormembrane fusionsurfactin

Identifiers

PMID30068648
PMCPMC6189506
OpenAlexW2887794952

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.