Observational studyNeurology2018
Assessment and comparison of the max-ICH score and ICH score by external validation.
Observational study in Neurology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06836141 (Silent Brain Infarcts in Spontaneous Intracerebral Hemorrhage as a Prognostic Biomarker for Vascular Contributions to Cognitive Impairment and Dementia), which is not on this map. Cited by 25 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Silent Brain Infarcts in Spontaneous Intracerebral Hemorrhage as a Prognostic Biomarker for Vascular Contributions to Cognitive Impairment and Dementia (VCID)
Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Guidelines for Neuroprognostication in Critically Ill Adults with Intracerebral Hemorrhage.Neurocritical care · 2024Guideline
- Methodological quality of multivariate prognostic models for intracranial haemorrhages in intensive care units: a systematic review.BMJ open · 2021Pooled it
- Efficacy of delivery of care with Tele-continuous EEG in critically ill patients: a multicenter randomized controlled trial (Tele-cRCT study) study.Critical care (London, England) · 2025Trial
- Comparative external validation of ICH prognostic scores for discharge outcomes in the RES-Q multinational quality registry.European stroke journal · 2026Article
- Neuromodulatory effects of voluntary-motor-effort-driven wrist-hand robot in sensorimotor dynamics after stroke.Journal of neuroengineering and rehabilitation · 2026Article
- Association Between Higher Insulin Resistance and Poor Short-Term Functional Outcome After Nonsurgical Intracerebral Hemorrhage.Journal of the American Heart Association · 2026Article
- Early care limitation after ICH in a population-based study: what drives clinicians' decisions?European stroke journal · 2026Article
- Social Factors Influencing Decision-Making in Intracerebral Haemorrhage: A Survey among Neurology Professionals.Cerebrovascular diseases (Basel, Switzerland) · 2026Article
- Short-term mortality prognosis in spontaneous intracranial hemorrhage: A retrospective study at 115 People's Hospital, HCMC, Vietnam.Journal of public health research · 2025Article
- A simple CT score predicts early neurological disability and survival in supratentorial intracerebral hemorrhage - The intracerebral mass and brain edema score (IMBES).Brain & spine · 2025Article
- Involvement of the posterior limb of the internal capsule independently predicts the prognosis of patients with basal ganglia and thalamic hemorrhage.Frontiers in neurology · 2024Article
- Prediction of poor outcome in stroke patients using radiomics analysis of intraparenchymal and intraventricular hemorrhage and clinical factors.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023Article
- Increased serum fibroblast growth factor 21 levels are associated with adverse clinical outcomes after intracerebral hemorrhage.Frontiers in neuroscience · 2023Article
- ANAID-ICH nomogram for predicting unfavorable outcome after intracerebral hemorrhage.CNS neuroscience & therapeutics · 2022Article
- Is using intracerebral hemorrhage scoring systems valid for mortality prediction in surgically treated patients?Neurosurgical review · 2021Article
- The Feasibility and Validity of Objective and Patient-Reported Measurements of Cognition During Early Critical Illness Recovery.Neurocritical care · 2021Article
- Temporal Evolution and Outcomes of Non-Traumatic Intracerebral Hemorrhage in Hospitalized Patients.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2021Observational
- Comparison of Conventional Intensive Care Scoring Systems and Prognostic Scores Specific for Intracerebral Hemorrhage in Predicting One-Year Mortality.Neurocritical care · 2021Article
- Identifying Modifiable Predictors of Patient Outcomes After Intracerebral Hemorrhage with Machine Learning.Neurocritical care · 2021Article
- New Prediction Models of Functional Outcome in Acute Intracerebral Hemorrhage: The dICH Score and uICH Score.Frontiers in neurology · 2021Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
objectiveWe tested the hypothesis that the maximally treated intracerebral hemorrhage (max-ICH) score is superior to the ICH score for characterizing mortality and functional outcome prognosis in patients with ICH, particularly those who receive maximal treatment.
methodsPatients presenting with spontaneous ICH were enrolled in a prospective observational study that collected demographic and clinical data. Mortality and functional outcomes were measured by using the modified Rankin Scale at 3 months. The ICH score and max-ICH score incorporate measures of symptom severity, age, hematoma volume, hematoma location, and intraventricular hemorrhage, with the max-ICH score also including a term for oral anticoagulation and having 16 score categories vs 11 for the ICH score. We compared the area under the receiver operating characteristic curve (AUC) for the ICH score and max-ICH score for both mortality and poor functional outcome, defined as modified Rankin Scale scores 4-6.
resultsWe analyzed outcomes for 372 patients, including 71 patients (19%) in whom care limitation/withdrawal of life support was instituted. Both the ICH score and max-ICH score showed good prognostic performance for 3-month mortality and poor functional outcomes in the full group as well as the subgroup with maximal treatment (i.e., no care limitations; AUC range 0.80-0.86), with no significant difference in AUC between the scores for either endpoint in either group.
conclusionsExternal validation with direct comparison of the ICH score and max-ICH score shows that their prognostic performance is not meaningfully different. Alternatives to simple scores are likely needed to improve prognostic estimates for patient care decisions.
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