Evidence map›Paper›PMID 30068597›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

Cutting Edge: IL-1R1 Mediates Host Resistance to

Andrea C Bohrer, Claire Tocheny, Maike Assmann, Vitaly V Ganusov, Katrin D Mayer-Barber

Open access · greenAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 42 citations in OpenAlex.

  1. Trial
  2. Protein kinase F regulates the virulence ofInfection and immunity · 2026
    Article
  3. Protein kinase F regulates the virulence ofbioRxiv : the preprint server for biology · 2025
    Article
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  16. A TNF-IL-1 circuit controlsbioRxiv : the preprint server for biology · 2023
    Article
  17. Article
  18. Co-infection of mice with SARS-CoV-2 andFrontiers in immunology · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Andrea C BohrerInflammation and Innate Immunity Unit, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892; and.ORCID 0000-0003-4268-4853
Claire TochenyInflammation and Innate Immunity Unit, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892; and.
Maike AssmannInflammation and Innate Immunity Unit, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892; and.ORCID 0000-0003-2669-9676
Vitaly V GanusovDepartment of Microbiology, University of Tennessee, Knoxville, TN 37996.ORCID 0000-0001-6572-1691
Katrin D Mayer-BarberInflammation and Innate Immunity Unit, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892; and mayerk@niaid.nih.gov.
National Institutes of Health · USUniversity of Tennessee at Knoxville · US

Funding

Innate inflammatory responses during pulmonary infectionsZIAAI001207 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI MAYER-BARBER, KATRIN · 2015 to 2025
$13.6M
Mathematical modeling of immune response to malariaR01GM118553 · NIGMS · UNIVERSITY OF TENNESSEE KNOXVILLE · PI GANUSOV, VITALY V. · 2017 to 2021
$1.6M
Intramural NIH HHS ZIA AI001207NIGMS NIH HHS R01 GM118553
6 · The paper itself

Abstract

IL-1R1 deficiency in mice causes severe susceptibility to

Indexed as

Immunity, InnateAnimalsLungMacrophagesMiceMice, KnockoutMycobacterium tuberculosisReceptors, Interleukin-1 Type ISignal TransductionTuberculosis, PulmonaryIL1R1 protein, mouseReceptors, Interleukin-1 Type I

Identifiers

PMID30068597
PMCPMC6125209
OpenAlexW2885355262

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.