Evidence map›Paper›PMID 30068535›Full record

ArticleJournal of clinical microbiology2018

PCR-Based Approach Targeting Mucorales-Specific Gene Family for Diagnosis of Mucormycosis.

Clara Baldin, Sameh S M Soliman, Heewon H Jeon, Sondus Alkhazraji, Teclegiorgis Gebremariam, Yiyou Gu, Vincent M Bruno, Oliver A Cornely, Helen L Leather, Michele W Sugrue and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 111 citations in OpenAlex.

  1. Article
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  6. Plasma Microbial Cell-free DNA Metagenomic Sequencing for Diagnosis of Invasive Fungal Diseases Among High-risk Outpatient and Inpatient Immunocompromised Hosts.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Recent Advances in Diagnostic Approaches for Mucormycosis.Journal of fungi (Basel, Switzerland) · 2024
    Review
  13. Review
  14. Molecular mechanisms that govern infection and antifungal resistance in Mucorales.Microbiology and molecular biology reviews : MMBR · 2024
    Review
  15. Article
  16. Review
  17. Review
  18. Review
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  20. Review

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 3 countries.

Clara BaldinDivision of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California at Los Angeles Medical Center, Torrance, California, USA.
Sameh S M SolimanSharjah Institute for Medical Research, and College of Pharmacy, University of Sharjah, Sharjah, United Arab Emirates.
Heewon H JeonDivision of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California at Los Angeles Medical Center, Torrance, California, USA.
Sondus AlkhazrajiDivision of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California at Los Angeles Medical Center, Torrance, California, USA.
Teclegiorgis GebremariamDivision of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California at Los Angeles Medical Center, Torrance, California, USA.
Yiyou GuDivision of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California at Los Angeles Medical Center, Torrance, California, USA.
Vincent M BrunoInstitute for Genome Sciences, Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Oliver A CornelyCologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, German Centre for Infection Research (DZIF), partner site Bonn-Cologne, and Department I of Internal Medicine, University Hospital of Cologne, Cologne, Germany.
Helen L LeatherDivsion of Hematology/Oncology, University of Florida College of Medicine, Gainesville, Florida, USA.
Michele W SugrueDivsion of Hematology/Oncology, University of Florida College of Medicine, Gainesville, Florida, USA.
John R WingardDivsion of Hematology/Oncology, University of Florida College of Medicine, Gainesville, Florida, USA.
David A StevensCalifornia Institute for Medical Research, San Jose, California, USA.
John E EdwardsDivision of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California at Los Angeles Medical Center, Torrance, California, USA.
Ashraf S IbrahimDivision of Infectious Diseases, Los Angeles Biomedical Research Institute at Harbor-University of California at Los Angeles Medical Center, Torrance, California, USA ibrahim@labiomed.org.
University of California, Los Angeles · USLos Angeles Medical Center · USUniversity of Florida · USCologne Excellence Cluster on Cellular Stress Responses in Aging Associated Diseases · DEFlorida College · USStanford University · USThe Lundquist Institute · USUniversity of Maryland, Baltimore · USUniversity of Sharjah · AE

Funding

Technology CoreU19AI110820 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI RASKO, DAVID A · 2014 to 2023
$36.5M
Novel Toxins and Receptors in Mucormycosis Pathogenesis and TreatmentR01AI063503 · NIAID · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI IBRAHIM, ASHRAF S. · 2006 to 2025
$7.3M
National Institute of Allergy and Infectious Diseases Extramural Activities N01AI70023NIAID NIH HHS R01 AI063503NIAID NIH HHS U19 AI110820
6 · The paper itself

Abstract

Mucormycosis is an aggressive, life-threatening infection caused by fungi in the order Mucorales. The current diagnosis of mucormycosis relies on mycological cultures, radiology and histopathology. These methods lack sensitivity and are most definitive later in the course of infection, resulting in the prevention of timely intervention. PCR-based approaches have shown promising potential in rapidly diagnosing mucormycosis. The spore coating protein homolog encoding

Indexed as

Polymerase Chain ReactionAnimalsAspergillosisDNA, FungalFungal ProteinsHumansMiceMucoralesMucormycosisReproducibility of ResultsSensitivity and SpecificityDNA, FungalFungal ProteinsCotHCunninghamelladiagnosisLichtheimiaMucorMucoralesRhizopus

Identifiers

PMID30068535
PMCPMC6156309
OpenAlexW2885103151

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.