Evidence map›Paper›PMID 30068527›Full record

ArticleGenetics2018

Comparing and Contrasting the Effects of

Emily Deutschman, Jacqueline R Ward, Kimberly T Ho-A-Lim, Tyler J Alban, Dongmei Zhang, Belinda Willard, Madeleine E Lemieux, Justin D Lathia, Michelle S Longworth

Open access · bronzeAbstract read
In one paragraph

Article in Genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Emily DeutschmanDepartment of Inflammation and Immunity, Lerner Research Institute of Cleveland Clinic Cleveland, OH, 44195.
Jacqueline R WardDepartment of Inflammation and Immunity, Lerner Research Institute of Cleveland Clinic Cleveland, OH, 44195.
Kimberly T Ho-A-LimDepartment of Molecular Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH 44195.
Tyler J AlbanDepartment of Cellular and Molecular Medicine, Lerner Research Institute of Cleveland Clinic, Cleveland, OH 44195.
Dongmei ZhangProteomics Core, Lerner Research Institute of Cleveland Clinic, Cleveland, OH 44195.
Belinda WillardProteomics Core, Lerner Research Institute of Cleveland Clinic, Cleveland, OH 44195.
Madeleine E LemieuxBioinfo, Plantagenet, ON K0B 1L0, Canada.
Justin D LathiaDepartment of Cellular and Molecular Medicine, Lerner Research Institute of Cleveland Clinic, Cleveland, OH 44195.
Michelle S LongworthDepartment of Inflammation and Immunity, Lerner Research Institute of Cleveland Clinic Cleveland, OH, 44195 longwom@ccf.org.ORCID 0000-0002-1313-1777
Case Western Reserve University · USCleveland Clinic Lerner College of Medicine · US

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Molecular Medicine Training ProgramT32GM088088 · NIGMS · CLEVELAND CLINIC LERNER COM-CWRU · PI SMITH, JONATHAN D · 2011 to 2020
$1.7M
Condensin-mediated genome organization and transcriptional regulationR01GM102400 · NIGMS · CLEVELAND CLINIC LERNER COM-CWRU · PI LONGWORTH, MICHELLE S · 2012 to 2016
$1.5M
LTQ-Orbitrap Velos instrumentS10RR031537 · NCRR · CLEVELAND CLINIC LERNER COM-CWRU · PI WILLARD, BELINDA BELLE · 2011 to 2011
$600k
Spinning Disk Confocoal MicroscopeS10RR026820 · NCRR · CLEVELAND CLINIC LERNER COM-CWRU · PI DRAZBA, JUDY · 2010 to 2010
$500k
NCRR NIH HHS S10 RR026820NCRR NIH HHS S10 RR031537NIGMS NIH HHS R01 GM102400NIGMS NIH HHS T32 GM088088NIH HHS P40 OD018537
6 · The paper itself

Abstract

The Condensin II complex plays important, conserved roles in genome organization throughout the cell cycle and in the regulation of gene expression. Previous studies have linked decreased Condensin II subunit expression with a variety of diseases. Here, we show that elevated levels of Condensin II subunits are detected in somatic cancers. To evaluate potential biological effects of elevated Condensin II levels, we overexpressed the Condensin II subunit, dCAP-D3 in

Indexed as

Adenosine TriphosphatasesAnimalsDNA-Binding ProteinsDrosophila melanogasterDrosophila ProteinsEmbryonic DevelopmentGene Expression Regulation, DevelopmentalMitosisMultiprotein ComplexesAdenosine Triphosphatasescondensin complexesDNA-Binding ProteinsDrosophila ProteinsMultiprotein ComplexesCAP-D3Condensin IIdevelopmentgene expressionmitosis

Identifiers

PMID30068527
PMCPMC6216582
OpenAlexW2886726921

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.