ArticleG3 (Bethesda, Md.)2018
GWAS with Heterogeneous Data: Estimating the Fraction of Phenotypic Variation Mediated by Gene Expression Data.
Article in G3 (Bethesda, Md.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Local Trade-Offs Shape Flower Size Evolution Across Arabidopsis thaliana Distribution.Molecular ecology · 2026Article
- Major alleles of CDCA7 shape CG methylation in Arabidopsis thaliana.Nature plants · 2025Article
- Conditional GWAS of non-CG transposon methylation in Arabidopsis thaliana reveals major polymorphisms in five genes.PLoS genetics · 2022Article
- Genome-wide mediation analysis: an empirical study to connect phenotype with genotype via intermediate transcriptomic data in maize.Genetics · 2022Article
- Evolution of flowering time in a selfing annual plant: Roles of adaptation and genetic drift.Ecology and evolution · 2022Article
- Genetic dissection of flowering time in flax (Linum usitatissimum L.) through single- and multi-locus genome-wide association studies.Molecular genetics and genomics : MGG · 2021Article
- Genetic architecture and adaptation of flowering time among environments.The New phytologist · 2021Article
- Gene regulatory networks controlled by FLOWERING LOCUS C that confer variation in seasonal flowering and life history.Journal of experimental botany · 2021Article
- Integrating Genome-Wide Association Analysis With Transcriptome Sequencing to Identify Candidate Genes Related to Blooming Time inFrontiers in plant science · 2021Article
- Article
- The GeneG3 (Bethesda, Md.) · 2020Article
- Epistasis Detection and Modeling for Genomic Selection in Cowpea (Frontiers in genetics · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intermediate phenotypes such as gene expression values can be used to elucidate the mechanisms by which genetic variation causes phenotypic variation, but jointly analyzing such heterogeneous data are far from trivial. Here we extend a so-called mediation model to handle the confounding effects of genetic background, and use it to analyze flowering time variation in
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.