ArticleThe British journal of ophthalmology2019
Peripheral capillary non-perfusion in treatment-naïve proliferative diabetic retinopathy associates with postoperative disease activity 6 months after panretinal photocoagulation.
Article in The British journal of ophthalmology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 17 citations in OpenAlex.
- Intraoperative Modified Peripheral Panretinal Photocoagulation in Proliferative Diabetic Retinopathy.Ophthalmology and therapy · 2026Article
- Grid-Based Software for Quantification of Diabetic Retinal Nonperfusion on Ultra-Widefield Fluorescein Angiography.Diagnostics (Basel, Switzerland) · 2025Article
- Optical coherence tomography angiography in diabetic retinopathy.Progress in retinal and eye research · 2023Review
- Diabetic retinopathy with extensively large area of capillary non-perfusion: characteristics and treatment outcomes.BMC ophthalmology · 2022Article
- Clinical Manifestations of Supra-Large Range Nonperfusion Area in Diabetic Retinopathy.International journal of clinical practice · 2022Article
- Longitudinal changes in retinal microvasculature after panretinal photocoagulation in diabetic retinopathy using swept-source OCT angiography.Scientific reports · 2021Article
- Quantitative analysis of retinal vasculature in normal eyes using ultra-widefield fluorescein angiography.International journal of ophthalmology · 2021Article
- Relationship Between Retinal Capillary Nonperfusion Area and Renal Function in Patients With Type 2 Diabetes.Investigative ophthalmology & visual science · 2020Article
- Factors predicting final visual outcome in quiescent proliferative diabetic retinopathy.Scientific reports · 2020Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimsWith the perspective to provide individualised panretinal laser photocoagulation (PRP) for proliferative diabetic retinopathy (PDR), we evaluated if retinal peripheral capillary non-perfusion (PCNP) and oximetry, as non-invasive markers of retinal metabolism and function, could predict disease activity 6 months after PRP.
methodsWe performed a prospective, interventional study of patients with treatment-naïve PDR. Retinal oximetry and ultra-widefield fluorescein angiography were performed at baseline (BL) and three (3M) and 6 months (6M) after PRP by a navigated laser system. At 6M follow-up, patients were divided according to disease activity: active or inactive.
resultsWe included 33 eyes, and 69.6% were men. At BL, the median age and duration of diabetes (with IQRs) were 51.6±23.4 and 20.0±15.0 years. Haemoglobin A
conclusionWe found the area of PCNP at all timepoints to be statistically larger in patients with active PDR 6 months after PRP treatment. Therefore, the area of PCNP, at baseline, may serve as a potential predictive marker for PDR activity after treatment.
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