Evidence map›Paper›PMID 30068364›Full record

ArticleParasites & vectors2018

Comparative performance of reference laboratory tests and in-clinic tests for Giardia in canine feces.

Jennifer Mizhquiri Barbecho, Dwight D Bowman, Janice L Liotta

Abstract readComparative Study
In one paragraph

Article in Parasites & vectors, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Microorganisms · 2023
    Review
  4. International journal for parasitology. Parasites and wildlife · 2022
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Giardia lamblia infection: review of current diagnostic strategies.Gastroenterology and hepatology from bed to bench · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jennifer Mizhquiri BarbechoCollege of Veterinary Medicine, Cornell University, C4-114 VMC, 930 Campus Rd, Ithaca, NY, 14853, USA.
Dwight D BowmanCollege of Veterinary Medicine, Cornell University, C4-114 VMC, 930 Campus Rd, Ithaca, NY, 14853, USA. DDB3@cornell.edu.
Janice L LiottaCollege of Veterinary Medicine, Cornell University, C4-114 VMC, 930 Campus Rd, Ithaca, NY, 14853, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe examined the performance of four in-clinic Giardia diagnostic tests by comparing results to three laboratory methods for detection of Giardia. A set of 177 fecal samples originally submitted to a commercial laboratory by veterinarians for routine ova and parasite (O&P) testing was used. Specimens were examined by direct immunofluorescence assay (DFA) for presence of Giardia cysts which served as the gold standard. Fecal samples were tested using a Giardia-specific cyst wall antigen microtiter plate format enzyme-linked immunosorbent assay (ELISA) and each of the in-clinic assays adhering to the package insert for each kit.

resultsEvaluated were four in-clinic antigen test kits: VetScan® Canine Giardia Rapid Test (Abaxis), Anigen® Rapid CPV-CCV-Giardia Antigen Test (BioNote), SNAP® Giardia Test (IDEXX) and Witness® Giardia Test (Zoetis). In the comparison of the in-clinic tests to the DFA standard test sensitivity ranged between 70.0-87.1%, and specificity ranged between 71.1-93.4%.

conclusionOf the tests evaluated here, the SNAP test had the highest sensitivity and specificity. The SNAP test had the highest percent positive and percent negative agreement when compared to the microtiter plate format ELISA and the O&P assay.

Indexed as

AnimalsAntigens, ProtozoanDog DiseasesDogsEnzyme-Linked Immunosorbent AssayFecesGiardiaGiardiasisReagent Kits, DiagnosticAntigens, ProtozoanReagent Kits, DiagnosticAntigen assayCanine diseaseFecal assayGiardiaGiardia diagnosticsIn-clinic diagnosticsPoint of care diagnostics

Identifiers

PMID30068364
PMCPMC6090814

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.