Evidence map›Paper›PMID 30068228›Full record

ReviewBiological research for nursing2018

Oxidative Stress and Preterm Birth: An Integrative Review.

Tiffany A Moore, Iman M Ahmad, Matthew C Zimmerman

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Biological research for nursing, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 3 pooled it
12.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 3 syntheses or guidelines pooled it, 136 citations in OpenAlex.

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  17. Research Progress of Ribosomal Proteins in Reproductive Development.International journal of molecular sciences · 2024
    Review
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  20. Article

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Tiffany A Moore1 College of Nursing, University of Nebraska Medical Center, Omaha, NE, USA.
Iman M Ahmad2 College of Allied Health Professions, University of Nebraska Medical Center, Omaha, NE, USA.
Matthew C Zimmerman3 College of Medicine, University of Nebraska Medical Center, Omaha, NE, USA.
University of Nebraska Medical Center · US

Funding

Physiologic Stress During Pregnancy on Maternal and Infant OutcomesK01NR014474 · NINR · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI MOORE, TIFFANY A · 2014 to 2016
$238k
NINR NIH HHS K01 NR014474
6 · The paper itself

Abstract

backgroundA variety of methods and measures have been used to quantify oxidative stress in clinical studies related to preterm birth (PTB), and studies have reported conflicting findings. No integrative reviews have been conducted.

objectiveTo describe specific molecules used as markers of oxidative stress and methods to measure these molecules and to review the literature for associations between oxidative stress and PTB specific to these molecules.

methodSystematic literature searches were conducted in June 2015 and updated in 2017 in databases from the Biomedical Reference Collection: Basic Edition, including MEDLINE and clinicaltrials.gov . Articles were included if they described original research published after 2009 and compared PTB or preterm premature rupture of membranes with term birth (TB).

resultsAbstracts ( n = 3,107) were reviewed for inclusion/exclusion criteria. Of these, 308 were full-text reviewed, and 30 articles were included in this review. All were identified as nonexperimental. The most common measurements of oxidative stress were quantification of total oxidant or antioxidant status or lipid peroxidation. Studies measuring reactive oxygen species or by-products of oxidative stress reported higher levels of these molecules for preterm specimens compared to TB specimens. Studies measuring antioxidants reported lower levels for these molecules in PTB specimens. Few of the studies had inconclusive findings. DISCUSSION: Findings suggest that an imbalance between oxidants and antioxidants may be associated with PTB. The measurements and findings to date limit interpretation and understanding. Research using multidimensional methods and multidisciplinary teams are necessary to advance research and practice.

Indexed as

AdultAntioxidantsBiomarkersFemaleHumansInfant, NewbornOxidative StressPregnancyPregnant PeoplePremature BirthReactive Oxygen SpeciesAntioxidantsBiomarkersReactive Oxygen Speciesantioxidantspremature birthreactive oxygen species

Identifiers

PMID30068228
PMCPMC6346316
OpenAlexW2887527191

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.