Evidence map›Paper›PMID 30067969›Full record

ArticleCell reports2018

Successful Reorganization of Category-Selective Visual Cortex following Occipito-temporal Lobectomy in Childhood.

Tina T Liu, Adrian Nestor, Mark D Vida, John A Pyles, Christina Patterson, Ying Yang, Fan Nils Yang, Erez Freud, Marlene Behrmann

Abstract read
In one paragraph

Article in Cell reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. With childhood hemispherectomy, one hemisphere can support-but is suboptimal for-word and face recognition.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Tina T LiuCenter for the Neural Basis of Cognition, Carnegie Mellon University and the University of Pittsburgh, Pittsburgh, PA, USA; Department of Psychology, Carnegie Mellon University, Pittsburgh, PA, USA.
Adrian NestorDepartment of Psychology, University of Toronto, Scarborough, Toronto, ON, Canada.
Mark D VidaCenter for the Neural Basis of Cognition, Carnegie Mellon University and the University of Pittsburgh, Pittsburgh, PA, USA; Department of Psychology, Carnegie Mellon University, Pittsburgh, PA, USA.
John A PylesCenter for the Neural Basis of Cognition, Carnegie Mellon University and the University of Pittsburgh, Pittsburgh, PA, USA; Department of Psychology, Carnegie Mellon University, Pittsburgh, PA, USA.
Christina PattersonDepartment of Pediatrics, University of Pittsburgh, Pittsburgh, PA, USA.
Ying YangCenter for the Neural Basis of Cognition, Carnegie Mellon University and the University of Pittsburgh, Pittsburgh, PA, USA; Machine Learning Department, School of Computer Science, Carnegie Mellon University, Pittsburgh, PA, USA.
Fan Nils YangDepartment of Psychology, Sun Yat-Sen University, Guangzhou, China; Center for Functional Neuroimaging & Department of Neurology, University of Pennsylvania, Philadelphia, PA, USA.
Erez FreudCenter for the Neural Basis of Cognition, Carnegie Mellon University and the University of Pittsburgh, Pittsburgh, PA, USA; Department of Psychology, Carnegie Mellon University, Pittsburgh, PA, USA.
Marlene BehrmannCenter for the Neural Basis of Cognition, Carnegie Mellon University and the University of Pittsburgh, Pittsburgh, PA, USA; Department of Psychology, Carnegie Mellon University, Pittsburgh, PA, USA. Electronic address: behrmann@cmu.edu.

Funding

REORGANIZATION OF VISUAL FUNCTION IN PATIENTS WITH POSTERIOR CORTICAL RESECTION: SELECTIVITY AND PLASTICITYR01EY027018 · NEI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Marlene Behrmann · 2017 to 2026
$3.2M
NEI NIH HHS R01 EY027018
6 · The paper itself

Abstract

Investigations of functional (re)organization in children who have undergone large cortical resections offer a unique opportunity to elucidate the nature and extent of cortical plasticity. We report findings from a 3-year investigation of a child, U.D., who underwent surgical removal of the right occipital and posterior temporal lobes at age 6 years 9 months. Relative to controls, post-surgically, U.D. showed age-appropriate intellectual performance and visuoperceptual face and object recognition skills. Using fMRI at five different time points, we observed a persistent hemianopia and no visual field remapping. In category-selective visual cortices, however, object- and scene-selective regions in the intact left hemisphere were stable early on, but regions subserving face and word recognition emerged later and evinced competition for cortical representation. These findings reveal alterations in the selectivity and topography of category-selective regions when confined to a single hemisphere and provide insights into dynamic functional changes in extrastriate cortical architecture.

Indexed as

Neuronal PlasticityPsychosurgeryChildCognitionDrug Resistant EpilepsyFacial RecognitionHumansLanguageMagnetic Resonance ImagingMaleTemporal LobeVisual Cortexcategory-selectivitychildhoodcortical organizationcortical resectionepilepsyface processinglobectomyplasticityvisuospatial performanceword processing

Identifiers

PMID30067969
PMCPMC6152879

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.