Evidence map›Paper›PMID 30067923›Full record

ReviewThe New England journal of medicine2018

Sequencing of Circulating Cell-free DNA during Pregnancy.

Diana W Bianchi, Rossa W K Chiu

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in The New England journal of medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 165 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
165citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

165 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  13. Extracellular heme:DNA complexes promote oxidative stress and inflammation during lupus-associated hemolysis.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  14. Article
  15. Cell-Free DNA-Based Theranostics for Inflammatory Disorders.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

105 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Diana W BianchiFrom the Prenatal Genomics and Fetal Therapy Section, Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD (D.W.B.); and the Li Ka Shing Institute of Health Sciences and the Department of Chemical Pathology, Chinese University of Hong Kong, Shatin, Hong Kong (R.W.K.C.).ORCID http://orcid.org/0000-0001-9270-5267
Rossa W K ChiuFrom the Prenatal Genomics and Fetal Therapy Section, Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD (D.W.B.); and the Li Ka Shing Institute of Health Sciences and the Department of Chemical Pathology, Chinese University of Hong Kong, Shatin, Hong Kong (R.W.K.C.).

Funding

Sequence Analysis of Circulating Cell-free DNA During PregnancyZIAHG200400 · NHGRI · NATIONAL HUMAN GENOME RESEARCH INSTITUTE · PI BIANCHI, DIANA · 2018 to 2025
$524k
Intramural NIH HHS ZIA HG200400
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell-Free Nucleic AcidsChromosome AberrationsFalse Negative ReactionsFalse Positive ReactionsFemaleFetusHumansMaleMutationPregnancyPrenatal DiagnosisSequence Analysis, DNACell-Free Nucleic Acids

Identifiers

PMID30067923
PMCPMC10123508

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.