ArticlePLoS neglected tropical diseases2018
The importance of dog population contact network structures in rabies transmission.
Article in PLoS neglected tropical diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Exploring Global Strategies to Combat Rabies: Addressing Limitations and Enhancing Effectiveness.Veterinary medicine and science · 2025Review
- Canine contact networks: A survey-based study of dog contacts and activities.The Canadian veterinary journal = La revue veterinaire canadienne · 2025Article
- Free-roaming dog populations and movement methodologies for global rabies elimination: knowns and unknowns - a scoping review.Frontiers in veterinary science · 2025Review
- A case-control study of risk factors for dog rabies in Northeast Tunisia.Open veterinary journal · 2024Article
- The Amazonian Tropical Bites Research Initiative, a hope for resolving zoonotic neglected tropical diseases in the One Health era.International health · 2023Article
- Modeling the effectiveness of targeting Rift Valley fever virus vaccination using imperfect network information.Frontiers in veterinary science · 2023Article
- The effects of geographical distributions of buildings and roads on the spatiotemporal spread of canine rabies: An individual-based modeling study.PLoS neglected tropical diseases · 2022Article
- Review
- Modelling the influence of naturally acquired immunity from subclinical infection on outbreak dynamics and persistence of rabies in domestic dogs.PLoS neglected tropical diseases · 2021Article
- Predictors of free-roaming domestic dogs' contact network centrality and their relevance for rabies control.Scientific reports · 2021Article
- Mathematical modelling and phylodynamics for the study of dog rabies dynamics and control: A scoping review.PLoS neglected tropical diseases · 2021Article
- Modelling the factors affecting the probability for local rabies elimination by strategic control.PLoS neglected tropical diseases · 2021Article
- Comparative Study of Free-Roaming Domestic Dog Management and Roaming Behavior Across Four Countries: Chad, Guatemala, Indonesia, and Uganda.Frontiers in veterinary science · 2021Article
- Evaluation of the Worldwide Occurrence of Rabies in Dogs and Cats Using a Simple and Homogenous Framework for Quantitative Risk Assessments of Rabies Reintroduction in Disease-Free Areas through Pet Movements.Veterinary sciences · 2020Article
- Movement patterns of free-roaming dogs on heterogeneous urban landscapes: Implications for rabies control.Preventive veterinary medicine · 2020Article
- Long-range movements coupled with heterogeneous incubation period sustain dog rabies at the national scale in Africa.PLoS neglected tropical diseases · 2020Article
- A Practical Introduction to Mechanistic Modeling of Disease Transmission in Veterinary Science.Frontiers in veterinary science · 2020Article
- Article
- Impact of One-Health framework on vaccination cost-effectiveness: A case study of rabies in Ethiopia.One health (Amsterdam, Netherlands) · 2019Article
- Rabies-induced behavioural changes are key to rabies persistence in dog populations: Investigation using a network-based model.PLoS neglected tropical diseases · 2019Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Canine rabies transmission was interrupted in N'Djaména, Chad, following two mass vaccination campaigns. However, after nine months cases resurged with re-establishment of endemic rabies transmission to pre-intervention levels. Previous analyses investigated district level spatial heterogeneity of vaccination coverage, and dog density; and importation, identifying the latter as the primary factor for rabies resurgence. Here we assess the impact of individual level heterogeneity on outbreak probability, effectiveness of vaccination campaigns and likely time to resurgence after a campaign. Geo-located contact sensors recorded the location and contacts of 237 domestic dogs in N'Djaména over a period of 3.5 days. The contact network data showed that urban dogs are socially related to larger communities and constrained by the urban architecture. We developed a network generation algorithm that extrapolates this empirical contact network to networks of large dog populations and applied it to simulate rabies transmission in N'Djaména. The model predictions aligned well with the rabies incidence data. Using the model we demonstrated, that major outbreaks are prevented when at least 70% of dogs are vaccinated. The probability of a minor outbreak also decreased with increasing vaccination coverage, but reached zero only when coverage was near total. Our results suggest that endemic rabies in N'Djaména may be explained by a series of importations with subsequent minor outbreaks. We show that highly connected dogs hold a critical role in transmission and that targeted vaccination of such dogs would lead to more efficient vaccination campaigns.
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