ArticlePlant signaling & behavior2018
WRINKLED1 as a novel 14-3-3 client: function of 14-3-3 proteins in plant lipid metabolism.
Article in Plant signaling & behavior, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- From wrinkled seeds to plant oil accumulation networks: the legacy of a Plant Physiology classic.Plant physiology · 2026Review
- 14-3-3 proteins: Central hubs in plant development and stress adaptation.Journal of integrative plant biology · 2026Review
- SUMO-specific proteases SPF1 and SPF2 negatively regulate seed oil synthesis by mediating WRI1 deSUMOylation.Plant communications · 2026Article
- A 14-3-3 modulator of seed weight and quality for unlocking the yield potential of soybean.Nature communications · 2025Article
- Functional Characterization of the 14-3-3 Gene Family in Alfalfa and the Role ofInternational journal of molecular sciences · 2024Article
- Potato virus Y viral protein 6K1 inhibits the interaction between defense proteins during virus infection.Plant physiology · 2024Article
- HEAT SHOCK PROTEIN 90.6 interacts with carbon and nitrogen metabolism components during seed development.Plant physiology · 2023Article
- Evidence and Metabolic Implications for a New Non-Canonical Role of Cu-Zn Superoxide Dismutase.International journal of molecular sciences · 2023Article
- Genome-Wide Identification and Expression Analysis of the 14-3-3 (TFT) Gene Family in Tomato, and the Role ofPlants (Basel, Switzerland) · 2022Article
- Pyruvate transporter BnaBASS2 impacts seed oil accumulation in Brassica napus.Plant biotechnology journal · 2022Article
- BnaPPT1 is essential for chloroplast development and seed oil accumulation in Brassica napus.Journal of advanced research · 2022Article
- Transcriptional regulation of oil biosynthesis in seed plants: Current understanding, applications, and perspectives.Plant communications · 2022Review
- Article
- Overexpression of WRINKLED1 improves the weight and oil content in seeds of flax (Frontiers in plant science · 2022Article
- The function of the WRI1-TCP4 regulatory module in lipid biosynthesis.Plant signaling & behavior · 2020Article
- Molecular Basis of Plant Oil Biosynthesis: Insights Gained From Studying the WRINKLED1 Transcription Factor.Frontiers in plant science · 2020Review
- Ca14-3-3 Interacts With CaWRKY58 to Positively Modulate Pepper Response to Low-Phosphorus Starvation.Frontiers in plant science · 2020Article
- WRINKLED1, a "Master Regulator" in Transcriptional Control of Plant Oil Biosynthesis.Plants (Basel, Switzerland) · 2019Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The conserved plant 14-3-3 proteins (14-3-3s) function by binding to phosphorylated client proteins to regulate their function. Previous studies indicate that 14-3-3s are involved in the regulation of plant primary metabolism; however, not much is known regarding the functions of 14-3-3s in plant oil biosynthesis. Our recent work shows that 14-3-3 plays a role in mediating plant oil biosynthesis through interacting with the transcription factor, WRINKLED1 (WRI1). WRI1 is critical for the transcriptional control of plant oil biosynthesis. Arabidopsis WRI1 physically interacts with 14-3-3s. Transient co-expression of AtWRI1 with 14-3-3s enhances plant oil biosynthesis in leaves of Nicotiana benthamiana. Transgenic plants overexpressing of a 14-3-3 show enhanced seed oil content. Co-expression of a 14-3-3 with AtWRI1 results in increased transcriptional activity and protein stability of AtWRI1. Our transcriptional regulation model supports a concept that interaction of a 14-3-3 with a transcription factor enhances the transcriptional activity through protein stabilization.
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