ArticleOrganic letters2018
N-N Bond Formation between Primary Amines and Nitrosos: Direct Synthesis of 2-Substituted Indazolones with Mechanistic Insights.
Article in Organic letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Continuous-flow photogeneration of nitrosobenzaldehydes enables indazolone formation.Communications chemistry · 2026Article
- Photoinitiator-free light-mediated crosslinking of dynamic polymer and pristine protein networks.Biomaterials science · 2024Article
- Continuous Flow Synthesis of Nitrosoarenes via Photochemical Rearrangement of Aryl Imines.The Journal of organic chemistry · 2024Article
- Synthesis and Anti-Inflammatory Activity ofMolecules (Basel, Switzerland) · 2023Article
- Intramolecular redox cyclization reaction access to cinnolines from 2-nitrobenzyl alcohol and benzylamineRSC advances · 2022Article
- A Redox Isomerization Strategy for Accessing Modular Azobenzene Photoswitches with Near Quantitative Bidirectional Photoconversion.Organic letters · 2019Article
- Davis-Beirut Reaction: Diverse Chemistries of Highly Reactive Nitroso Intermediates in Heterocycle Synthesis.Accounts of chemical research · 2019Review
- Davis-Beirut Reaction: A Photochemical Brønsted Acid Catalyzed Route toOrganic letters · 2019Article
- Rapid and halide compatible synthesis of 2-RSC advances · 2019Article
- Accessing Multiple Classes of 2 H-Indazoles: Mechanistic Implications for the Cadogan and Davis-Beirut Reactions.Journal of the American Chemical Society · 2019Article
- Photochemical Preparation of 1,2-Dihydro-3 H-indazol-3-ones in Aqueous Solvent at Room Temperature.The Journal of organic chemistry · 2018Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
A concise, one-step route to indazolones from primary alkyl amines and o-nitrobenzyl alcohols is reported. The key step in this readily scalable indazolone forming process involves base-mediated in situ o-nitrobenzyl alcohol → o-nitrosobenzaldehyde conversion. Although this functional group interconversion is known to be useful for 2 H-indazole synthesis, its reactivity was modulated for indazolone formation.
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Registered trials
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