Evidence map›Paper›PMID 30066655›Full record

ArticleBMC medical informatics and decision making2018

OC-2-KB: integrating crowdsourcing into an obesity and cancer knowledge base curation system.

Juan Antonio Lossio-Ventura, William Hogan, François Modave, Yi Guo, Zhe He, Xi Yang, Hansi Zhang, Jiang Bian

Abstract read
In one paragraph

Article in BMC medical informatics and decision making, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Machine learning in healthcare citizen science: A scoping review.International journal of medical informatics · 2025
    Article
  3. Article
  4. Knowledge-Based Biomedical Data Science.Annual review of biomedical data science · 2020
    Article
  5. Article
  6. Article
  7. Article
  8. STAT: A Web-based Semantic Text Annotation Tool to Assist Building Mental Health Knowledge Base.Proceedings. IEEE International Conference on Healthcare Informatics · 2019
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Juan Antonio Lossio-VenturaHealth Outcomes & Biomedical Informatics, College of Medicine, University of Florida, 2004 Mowry Road, Gainesville, FL, 32610, USA.
William HoganHealth Outcomes & Biomedical Informatics, College of Medicine, University of Florida, 2004 Mowry Road, Gainesville, FL, 32610, USA.
François ModaveHealth Outcomes & Biomedical Informatics, College of Medicine, University of Florida, 2004 Mowry Road, Gainesville, FL, 32610, USA.
Yi GuoHealth Outcomes & Biomedical Informatics, College of Medicine, University of Florida, 2004 Mowry Road, Gainesville, FL, 32610, USA.
Zhe HeSchool of Information, Florida State University, 142 Collegiate Loop, Tallahassee, FL, 32306, USA.
Xi YangHealth Outcomes & Biomedical Informatics, College of Medicine, University of Florida, 2004 Mowry Road, Gainesville, FL, 32610, USA.
Hansi ZhangHealth Outcomes & Biomedical Informatics, College of Medicine, University of Florida, 2004 Mowry Road, Gainesville, FL, 32610, USA.
Jiang BianHealth Outcomes & Biomedical Informatics, College of Medicine, University of Florida, 2004 Mowry Road, Gainesville, FL, 32610, USA. bianjiang@ufl.edu.

Funding

Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
NCATS NIH HHS UL1 TR001427
6 · The paper itself

Abstract

backgroundThere is strong scientific evidence linking obesity and overweight to the risk of various cancers and to cancer survivorship. Nevertheless, the existing online information about the relationship between obesity and cancer is poorly organized, not evidenced-based, of poor quality, and confusing to health information consumers. A formal knowledge representation such as a Semantic Web knowledge base (KB) can help better organize and deliver quality health information. We previously presented the OC-2-KB (Obesity and Cancer to Knowledge Base), a software pipeline that can automatically build an obesity and cancer KB from scientific literature. In this work, we investigated crowdsourcing strategies to increase the number of ground truth annotations and improve the quality of the KB.

methodsWe developed a new release of the OC-2-KB system addressing key challenges in automatic KB construction. OC-2-KB automatically extracts semantic triples in the form of subject-predicate-object expressions from PubMed abstracts related to the obesity and cancer literature. The accuracy of the facts extracted from scientific literature heavily relies on both the quantity and quality of the available ground truth triples. Thus, we incorporated a crowdsourcing process to improve the quality of the KB.

resultsWe conducted two rounds of crowdsourcing experiments using a new corpus with 82 obesity and cancer-related PubMed abstracts. We demonstrated that crowdsourcing is indeed a low-cost mechanism to collect labeled data from non-expert laypeople. Even though individual layperson might not offer reliable answers, the collective wisdom of the crowd is comparable to expert opinions. We also retrained the relation detection machine learning models in OC-2-KB using the crowd annotated data and evaluated the content of the curated KB with a set of competency questions. Our evaluation showed improved performance of the underlying relation detection model in comparison to the baseline OC-2-KB.

conclusionsWe presented a new version of OC-2-KB, a system that automatically builds an evidence-based obesity and cancer KB from scientific literature. Our KB construction framework integrated automatic information extraction with crowdsourcing techniques to verify the extracted knowledge. Our ultimate goal is a paradigm shift in how the general public access, read, digest, and use online health information.

Indexed as

CrowdsourcingKnowledge BasesNeoplasmsObesityData CurationEvidence-Based MedicineHumansInformation Storage and RetrievalMachine LearningPubMedSemanticsSoftwareBiomedical named-entity recognitionCancerCrowdsourcingInformation extractionObesityRelation extractionSemantic web knowledge base

Identifiers

PMID30066655
PMCPMC6069686

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.