Evidence map›Paper›PMID 30066648›Full record

ArticleBMC medical informatics and decision making2018

Using natural language processing methods to classify use status of dietary supplements in clinical notes.

Yadan Fan, Rui Zhang

Abstract read
In one paragraph

Article in BMC medical informatics and decision making, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. AI-Based Automation for Medication Reconciliation: Scoping Review.Journal of medical Internet research · 2026
    Article
  2. Article
  3. Article
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  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Toward Understanding Clinical Context of Medication Change Events in Clinical Narratives.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2021
    Article
  11. Assessing the enrichment of dietary supplement coverage in the Unified Medical Language System.Journal of the American Medical Informatics Association : JAMIA · 2020
    Article
  12. Review
  13. iDISK: the integrated DIetary Supplements Knowledge base.Journal of the American Medical Informatics Association : JAMIA · 2020
    Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yadan FanInstitute for Health Informatics, University of Minnesota, Minneapolis, MN, USA.
Rui ZhangInstitute for Health Informatics, University of Minnesota, Minneapolis, MN, USA. zhan1386@umn.edu.

Funding

University of Minnesota Clinical and Translational Science Institute (UMN CTSI)UL1TR000114 · NCATS · UNIVERSITY OF MINNESOTA · PI BLAZAR, BRUCE R · 2012 to 2015
$35.0M
A Translational Informatics Framework to Mine Efficacy and Safety of Dietary SupplementsR01AT009457 · NCCIH · UNIVERSITY OF MINNESOTA · PI RUI ZHANG · 2017 to 2026
$4.1M
NCATS NIH HHS UL1 TR000114NCCIH NIH HHS R01 AT009457
6 · The paper itself

Abstract

backgroundDespite widespread use, the safety of dietary supplements is open to doubt due to the fact that they can interact with prescribed medications, leading to dangerous clinical outcomes. Electronic health records (EHRs) provide a potential way for active pharmacovigilance on dietary supplements since a fair amount of dietary supplement information, especially those on use status, can be found in clinical notes. Extracting such information is extremely significant for subsequent supplement safety research.

methodsIn this study, we collected 2500 sentences for 25 commonly used dietary supplements and annotated into four classes: Continuing (C), Discontinued (D), Started (S) and Unclassified (U). Both rule-based and machine learning-based classifiers were developed on the same training set and evaluated using the hold-out test set. The performances of the two classifiers were also compared.

resultsThe rule-based classifier achieved F-measure of 0.90, 0.85, 0.90, and 0.86 in C, D, S, and U status, respectively. The optimal machine learning-based classifier (Maximum Entropy) achieved F-measure of 0.90, 0.92, 0.91 and 0.88 in C, D, S, and U status, respectively. The comparison result shows that the machine learning-based classifier has a better performance, which is more efficient and scalable especially when the sample size doubles.

conclusionsMachine learning-based classifier outperforms rule-based classifier in categorization of the use status of dietary supplements in clinical notes. Future work includes applying deep learning methods and developing a hybrid system to approach use status classification task.

Indexed as

Dietary SupplementsNatural Language ProcessingDocumentationElectronic Health RecordsHumansMachine LearningClinical notesDietary supplementsMachine learning-based classificationNatural language processingRule-based methodUse status

Identifiers

PMID30066648
PMCPMC6069512

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.