ArticleNeuroradiology2018
Visual cortex neural activity alteration in cervical spondylotic myelopathy patients: a resting-state fMRI study.
Article in Neuroradiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 4 of them syntheses that pooled it.
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Who cites it
36 citing papers in PubMed, 4 syntheses or guidelines pooled it, 43 citations in OpenAlex.
- Beyond the aging spine - a systematic review of functional changes in the human brain in cervical spondylotic myelopathy.GeroScience · 2024Pooled it
- Meta-analysis of resting-state fMRI in cervical spondylosis patients using AES-SDM.Frontiers in neurology · 2024Pooled it
- Abnormalities of brain structure and function in cervical spondylosis: a multi-modal voxel-based meta-analysis.Frontiers in neuroscience · 2024Pooled it
- Brain MRI changes in degenerative cervical myelopathy: a systematic review.EBioMedicine · 2024Pooled it
- Increased cervical spinal cord signal intensity corresponds to specific cerebellar and cerebral functional changes in degenerative cervical myelopathy patients.Scientific reports · 2026Article
- Article
- Alterations in resting-state brain connectivity in patients with cervical spondylotic myelopathy: an fNIRS study.Acta neurochirurgica · 2025Article
- Functional and structural brain remodeling in patients with degenerative cervical myelopathy following cervical decompression surgery.Communications medicine · 2025Article
- Altered brain network centrality in patients with cervical spondylotic myelopathy: insights from resting-state fMRI.Frontiers in neurology · 2025Article
- Fractional amplitude of low-frequency fluctuation alterations in patients with cervical spondylotic myelopathy: a resting-state fMRI study.Neuroradiology · 2024Article
- Neurodegeneration within the rostral spinal cord is associated with brain gray matter volume atrophy in the early stage of cervical spondylotic myelopathy.Spinal cord · 2024Article
- Systematic investigation of cerebellar functional alterations and their association with surgical outcomes in patients with degenerative cervical myelopathy: a resting-state fMRI study.La Radiologia medica · 2024Article
- Resting-state functional magnetic resonance imaging indices are related to electrophysiological dysfunction in degenerative cervical myelopathy.Scientific reports · 2024Article
- Voxel- and tensor-based morphometry with machine learning techniques identifying characteristic brain impairment in patients with cervical spondylotic myelopathy.Frontiers in neurology · 2024Article
- Utility of MRI in Quantifying Tissue Injury in Cervical Spondylotic Myelopathy.Journal of clinical medicine · 2023Review
- Preoperative pain hypersensitivity is associated with axial pain after posterior cervical spinal surgeries in degenerative cervical myelopathy patients: a preliminary resting-state fMRI study.Insights into imaging · 2023Article
- Cervicogenic visual dysfunction: an understanding of its pathomechanism.Medicine and pharmacy reports · 2023Review
- Outcomes of Degenerative Cervical Myelopathy From The Perspective of Persons Living With the Condition: Findings of a Semistructured Interview Process With Partnered Internet Survey.Global spine journal · 2022Article
- A New Framework for Investigating the Biological Basis of Degenerative Cervical Myelopathy [AO Spine RECODE-DCM Research Priority Number 5]: Mechanical Stress, Vulnerability and Time.Global spine journal · 2022Article
- Dynamic and Static Amplitude of Low-Frequency Fluctuation Is a Potential Biomarker for Predicting Prognosis of Degenerative Cervical Myelopathy Patients: A Preliminary Resting-State fMRI Study.Frontiers in neurology · 2022Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
purposeWe sought to investigate visual cortex neural activity and functional connectivity (FC) alterations in cervical spondylotic myelopathy (CSM) patients using resting-state fMRI (rs-fMRI) and to explore the relationships of these alterations with visual disorder.
methodsTwenty-seven CSM patients and 11 healthy controls were recruited as the study and control groups. The amplitude of low-frequency fluctuations (ALFF) and regional homogeneity (ReHo) values were calculated to represent neural activity, seed-based correlation analysis (SCA) was performed to analyze the FC of visual cortex, and the outcomes were compared between groups. The preoperative best-corrected visual acuity (pre-BCVA) and postoperative BCVA (post-BCVA) of study groups were measured. Correlation analyses of the ALFF/ReHo values with the preoperative and postoperative BCVAs were performed. Correlations of the bilateral BCVAs with the ipsilateral and contralateral visual cortex neural activities were performed.
resultsThe ALFF/ReHo values were decreased in the occipital lobe and increased in the cerebellar posterior lobe in the study group (P < 0.05). Increased FC was demonstrated between Brodmann's area 17 and posterior cingulate lobe (P < 0.05). Postoperatively, the BCVAs were ameliorated in 22 oculi dexter (ODs) and 20 oculi sinister (OSs) in the study group. Positive correlations between neural activity in the visual cortex and the preoperative and postoperative BCVAs were detected in the study group. The bilateral BCVAs were positively correlated with either the ipsilateral or contralateral visual cortex neural activity.
conclusionBoth ALFF/ReHo value changes and positive correlations of these changes with BCVA were demonstrated in CSM. The FC between the visual cortex and posterior cingulate lobe was also increased in CSM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.